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Fig. 6 | BMC Medical Research Methodology

Fig. 6

From: Using joint models to disentangle intervention effect types and baseline confounding: an application within an intervention study in prodromal Alzheimer’s disease with Fortasyn Connect

Fig. 6

Separate effects as estimated by the joint model for CDR-SB. The separate components exp(γ1) (direct effect; dashed line), exp(α×β2) (indirect constant effect; solid line) and exp(α×β3×t) (indirect time-varying effect; dot dashed line), that together form the hazard ratio for the total intervention effect as estimated from the joint model for CDR-SB, plotted as separate effects in a without and in b with correction for baseline MMSE in the survival sub-model

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