BMC Medical Research Methodology

Table 1 Results for the standard joint model for CDR-SB

From: Using joint models to disentangle intervention effect types and baseline confounding: an application within an intervention study in prodromal Alzheimer’s disease with Fortasyn Connect

	a) Without baseline MMSE		b) With baseline MMSE
	Coefficient (SE)	p Value	Coefficient (SE)	p Value
Longitudinal sub-model:
Time β₁	0.609 (0.047)	0.000	0.605 (0.047)	0.000
Fortasyn β₂	0.071 (0.077)	0.361	0.077 (0.077)	0.321
Time × Fortasyn β₃	-0.233 (0.069)	0.001	-0.234 (0.069)	0.001
Bmmse β₄	-0.122 (0.015)	0.000	-0.110 (0.016)	0.000
	Log Hazard (SE)	p Value	Log Hazard (SE)	p Value
Survival sub-model:
Fortasyn γ₁	0.394 (0.204)	0.053	0.125 (0.210)	0.553
Ass. α	0.701 (0.077)	0.000	0.664 (0.083)	0.000
Bmmse γ₂	-	-	-0.228 (0.050)	0.000

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ISSN: 1471-2288

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