Skip to main content

Table 2 Results for the different types of joint models for NTB memory domain

From: Using joint models to disentangle intervention effect types and baseline confounding: an application within an intervention study in prodromal Alzheimer’s disease with Fortasyn Connect

 

a) Current value

b) Current value plus slope

c) Cumulative effect

 

Coefficient (SE)

p Value

Coefficient (SE)

p Value

Coefficient (SE)

p Value

Longitudinal sub-model:

      

Time β1

-0.101 (0.030)

0.001

-0.128 (0.030)

0.000

-0.092 (0.029)

0.002

Fortasyn β2

0.042 (0.082)

0.617

0.039 (0.083)

0.640

0.042 (0.083)

0.610

Time × Fortasyn β3

0.052 (0.043)

0.219

0.049 (0.043)

0.254

0.054 (0.042)

0.192

Bmmse β4

0.160 (0.021)

0.000

0.159 (0.021)

0.000

0.158 (0.021)

0.000

 

Log Hazard (SE)

p Value

Log Hazard (SE)

p Value

Log Hazard (SE)

p Value

Survival sub-model:

      

Fortasyn γ1

0.154 (0.203)

0.449

0.513 (0.387)

0.185

0.112 (0.198)

0.573

Ass. α1

-1.214 (0.174)

0.000

-1.162 (0.341)

0.001

-

-

Ass. slope α2

-

-

-6.792 (1.854)

0.000

-

-

Ass. AUC α3

-

-

-

-

-0.671 (0.118)

0.000

Bmmse γ2

-0.098 (0.057)

0.085

-0.156 (0.088)

0.078

-0.163 (0.055)

0.003