Fig. 4
From: Patient recruitment strategies for adaptive enrichment designs with time-to-event endpoints
Comparison of expected numbers of patients in O for various recruitment strategies. Boxplots with circles (blue), squares (red), and triangles (green) show the results using each recruitment method. Stars (yellow) represent means. The expected number of patients under the non-enriched design was set to 330. R, recruitment period; F, follow-up period; O, overall population; P, biomarker-positive population