Fig. 5
From: Patient recruitment strategies for adaptive enrichment designs with time-to-event endpoints
Comparison of expected numbers of patients in P for various recruitment strategies. Boxplots with circles (blue), squares (red), and triangles (green) show the results using each recruitment method. Stars (yellow) represent means. The expected number of patients in O under the non-enriched design was set to 330. The expected number of patients in P was 165 since the prevalence of P among O was set to 50%. R, recruitment period; F, follow-up period; O, overall population; P, biomarker-positive population