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Fig. 7 | BMC Medical Research Methodology

Fig. 7

From: Patient recruitment strategies for adaptive enrichment designs with time-to-event endpoints

Fig. 7

Comparison between timing of the interim analysis and the accuracy of interim hazard ratio for P. Boxplots with circles (black) show trade-off between timing of the interim analysis and the accuracy of interim hazard ratio for P. Stars (yellow), triangles (red), and squares (green) represent the expected number of patients using patient recruitment strategies. R, recruitment period; F, follow-up period; O, overall population; P, biomarker-positive population

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