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Table 3 Four functions applied to define the thresholds at each of the interim analyses

From: A Bayesian non-inferiority approach using experts’ margin elicitation – application to the monitoring of safety events

1 A uniform function: \(\tau ^{l}_{j} = \tau *^{11}_{j}\) for all l(1,11).
2 A linear function: \(\tau ^{l}_{j} = a \times l + b\),
3 A linear function with an exponential transformation: \(\tau ^{l}_{j} = a \times exp^{l} + b\),
4 A linear function with a logarithm transformation: \(\tau ^{l}_{j} = a \times log(l) + b\).