Table 5 Results of the association parameter α estimated from the TVCM and joint model fitted to data generated considering slight and gross misspecifications of the longitudinal trajectories (scenarios 7 and 8 of Table 1), σε∈(0.1,0.3,0.5) with CV ∈(3.1%,9.4%,15.6%) and the true α=0.3
Slight misspecification | Gross misspecification | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
σε | Model | Est | ESE | ASE | %Bias | CP | Est | ESE | ASE | %Bias | CP |
0.1 | TVCM(1x/week) | 0.295 | 0.056 | 0.056 | -1.7 | 95 | 0.297 | 0.055 | 0.056 | -1.0 | 95 |
TVCM(4x/week) | 0.309 | 0.054 | 0.055 | 3.0 | 96 | 0.310 | 0.053 | 0.054 | 3.3 | 96 | |
joint model | 0.297 | 0.209 | 0.060 | -1.0 | 92 | 0.280 | 0.222 | 0.059 | -6.7 | 91 | |
0.3 | TVCM(1x/week) | 0.277 | 0.054 | 0.054 | -7.7 | 93 | 0.280 | 0.053 | 0.054 | -6.7 | 93 |
TVCM(4x/week) | 0.292 | 0.051 | 0.053 | -2.7 | 95 | 0.294 | 0.051 | 0.052 | -2.0 | 95 | |
joint model | 0.284 | 0.291 | 0.067 | -5.3 | 91 | 0.273* | 0.290 | 0.059 | -9.0 | 91 | |
0.5 | TVCM(1x/week) | 0.249 | 0.050 | 0.051 | -17 | 83 | 0.252 | 0.050 | 0.051 | -16 | 84 |
TVCM(4x/week) | 0.264 | 0.047 | 0.050 | -12 | 89 | 0.266 | 0.047 | 0.049 | -11 | 90 | |
joint model | 0.265 | 0.192 | 0.071 | -12 | 91 | 0.265* | 0.167 | 0.065 | -12 | 91 | |