Table 1 Characteristics of REGARDS participants

Eligible REGARDS Participants

HF-Free Cohort

Suspected HF

Number

28,884

25,759

3125

Age, mean (SD)

64.9 (9.4)

64.5 (9.3)

68.4 (9.3)

Female Sex

15,875 (55.0%)

14,161 (55.0%)

1714 (54.9%)

African American

11,823 (40.9%)

10,295 (40.0%)

1528 (48.9%)

BMI, mean (SD)

29.3 (6.2)

28.9 (5.9)

32.3 (7.4)

Coronary artery disease^a

5040 (17.6%)

3711 (14.5%)

1329 (43.2%)

Myocardial infarction^a

3571 (12.5%)

2605 (10.2%)

966 (31.5%)

Atrial fibrillation

2540 (8.8%)

1894 (7.4%)

646 (20.7%)

Stroke^a

1813 (6.3%)

1374 (5.4%)

439 (14.1%)

Diabetes^a

6078 (21.8%)

4684 (18.9%)

1394 (46.3%)

ACR ≥ 30^a

4154 (15.1%)

3318 (13.5%)

836 (28.6%)

eGFR < 60^a

3139 (11.3%)

2277 (9.2%)

862 (29.4%)

Hypertension

17,101 (59.2%)

14,704 (57.1%)

2397 (76.7%)

Dyslipidemia^a

16,495 (59.3%)

14,358 (57.8%)

2137 (71.3%)

Chronic lung disease

2656 (9.2%)

2159 (8.4%)

497 (15.9%)

Validation Cohort

HF-Free Cohort

Suspected HF

Number

10,059

8492

1567

Age, mean (SD)

71.4 (7.3)

71.3 (7.2)

71.6 (8.1)

Female Sex

5160 (51.3%)

4355 (51.3%)

805 (51.4%)

African American

3519 (35.0%)

2842 (33.5%)

677 (43.2%)

BMI, mean (SD)

28.7 (5.9)

28.2 (5.5)

31.4 (7.0)

Coronary artery disease

2517 (25.0%)

1764 (20.8%)

753 (48.1%)

Myocardial infarction

1693 (16.8%)

1169 (13.8%)

524 (33.4%)

Atrial fibrillation

1144 (11.4%)

792 (9.3%)

352 (22.5%)

Stroke

904 (9.0%)

658 (7.7%)

246 (15.7%)

Diabetes

2407 (23.9%)

1713 (20.2%)

694 (44.3%)

ACR ≥ 30

1767 (17.6%)

1327 (15.6%)

440 (28.1%)

eGFR < 60

2213 (22%)

1628 (19.2%)

585 (37.3%)

Hypertension

6652 (66.1%)

5458 (64.3%)

1194 (76.2%)

Dyslipidemia

6147 (61.1%)

5069 (59.7%)

1078 (68.8%)

Chronic lung disease

1100 (10.9%)

834 (9.8%)

266 (17.0%)