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Table 1 Characteristics of REGARDS participants

From: Assembling and validating a heart failure-free cohort from the Reasons for Geographic and Racial Differences in Stroke (REGARDS) study

A. Among eligible REGARDS participants
 Eligible REGARDS ParticipantsHF-Free CohortSuspected HF
Number28,88425,7593125
Age, mean (SD)64.9 (9.4)64.5 (9.3)68.4 (9.3)
Female Sex15,875 (55.0%)14,161 (55.0%)1714 (54.9%)
African American11,823 (40.9%)10,295 (40.0%)1528 (48.9%)
BMI, mean (SD)29.3 (6.2)28.9 (5.9)32.3 (7.4)
Coronary artery diseasea5040 (17.6%)3711 (14.5%)1329 (43.2%)
Myocardial infarctiona3571 (12.5%)2605 (10.2%)966 (31.5%)
Atrial fibrillation2540 (8.8%)1894 (7.4%)646 (20.7%)
Strokea1813 (6.3%)1374 (5.4%)439 (14.1%)
Diabetesa6078 (21.8%)4684 (18.9%)1394 (46.3%)
ACR ≥ 30a4154 (15.1%)3318 (13.5%)836 (28.6%)
eGFR < 60a3139 (11.3%)2277 (9.2%)862 (29.4%)
Hypertension17,101 (59.2%)14,704 (57.1%)2397 (76.7%)
Dyslipidemiaa16,495 (59.3%)14,358 (57.8%)2137 (71.3%)
Chronic lung disease2656 (9.2%)2159 (8.4%)497 (15.9%)
B. Among Medicare based Validation Cohort
 Validation CohortHF-Free CohortSuspected HF
Number10,05984921567
Age, mean (SD)71.4 (7.3)71.3 (7.2)71.6 (8.1)
Female Sex5160 (51.3%)4355 (51.3%)805 (51.4%)
African American3519 (35.0%)2842 (33.5%)677 (43.2%)
BMI, mean (SD)28.7 (5.9)28.2 (5.5)31.4 (7.0)
Coronary artery disease2517 (25.0%)1764 (20.8%)753 (48.1%)
Myocardial infarction1693 (16.8%)1169 (13.8%)524 (33.4%)
Atrial fibrillation1144 (11.4%)792 (9.3%)352 (22.5%)
Stroke904 (9.0%)658 (7.7%)246 (15.7%)
Diabetes2407 (23.9%)1713 (20.2%)694 (44.3%)
ACR ≥ 301767 (17.6%)1327 (15.6%)440 (28.1%)
eGFR < 602213 (22%)1628 (19.2%)585 (37.3%)
Hypertension6652 (66.1%)5458 (64.3%)1194 (76.2%)
Dyslipidemia6147 (61.1%)5069 (59.7%)1078 (68.8%)
Chronic lung disease1100 (10.9%)834 (9.8%)266 (17.0%)
  1. aPercentages were determined after excluding participants with missing data for the given variable
  2. Abbreviations
  3. ACR Albumin-to-creatinine ratio
  4. BMI Body mass index
  5. eGFR Estimated glomerular filtration rate
  6. HF Heart failure
  7. REGARDS REasons for Geographic And Racial Differences in Stroke
  8. SD Standard deviation