Algorithm | TP | FP | FN | TN | Sensitivity | Specificity | PPV | NPV | Kappa | Type 1 Proportion (%) | |
---|---|---|---|---|---|---|---|---|---|---|---|
Calculated | True | ||||||||||
All Ages | |||||||||||
Ratio of type 1 to type 2 codes ≥ 0.5 (A) | 50 | 97 | 10 | 10,039 | 83.3 (71.5, 91.7) | 99.0 (98.8, 99.2) | 34.0 (26.4, 42.3) | 99.9 (99.8, 100.0) | 0.48 | 1.4 | 0.6 |
Ratio of type 1 to type 2 codes ≥ 4 (B) | 43 | 32 | 17 | 10,104 | 71.7 (58.6, 82.5) | 99.7 (99.6, 99.8) | 57.3 (45.4, 68.7) | 99.8 (99.7, 99.9) | 0.63 | 0.7 | |
At least 1 insulin prescription within 90 days (C) | 58 | 615 | 2 | 9521 | 96.7 (88.5, 99.6) | 93.9 (93.5, 94.4) | 8.6 (6.6, 11.0) | 100.0 (99.9, 100.0) | 0.15 | 6.6 | |
Multiple daily injections with no other glucose-lowering medication prescription (D) | 32 | 9 | 28 | 10,127 | 53.3 (40.0, 66.3) | 99.9 (99.8, 100.0) | 78.0 (62.4, 89.4) | 99.7 (99.6, 99.8) | 0.63 | 0.4 | |
A and C | 49 | 52 | 11 | 10,084 | 81.7 (69.6, 90.5) | 99.5 (99.3, 99.6) | 48.5 (38.4, 58.7) | 99.9 (99.8, 99.9) | 0.61 | 1.0 | |
A and D | 28 | 5 | 32 | 10,131 | 46.7 (33.7, 60.0) | 100.0 (99.9, 100.0) | 84.8 (68.1, 94.9) | 99.7 (99.6, 99.8) | 0.60 | 0.3 | |
B and C‡ | 42 | 19 | 18 | 10,117 | 70.0 (56.8, 81.2) | 99.8 (99.7, 99.9) | 68.9 (55.7, 80.1) | 99.8 (99.7, 99.9) | 0.69 | 0.6 | |
B and D† | 25 | 4 | 35 | 10,132 | 41.7 (29.1, 55.1) | 100.0 (99.9, 100.0) | 86.2 (68.3, 96.1) | 99.7 (99.5, 99.8) | 0.56 | 0.3 | |
A or C | 59 | 660 | 1 | 9476 | 98.3 (91.1, 100.0) | 93.5 (93.0, 94.0) | 8.2 (6.3, 10.5) | 100.0 (99.9, 100.0) | 0.14 | 7.1 | |
A or D | 54 | 101 | 6 | 10,035 | 90.0 (79.5, 96.2) | 99.0 (98.8, 99.2) | 34.8 (27.4, 42.9) | 99.9 (99.9, 100.0) | 0.50 | 1.5 | |
B or C* | 59 | 628 | 1 | 9508 | 98.3 (91.1, 100.0) | 93.8 (93.3, 94.3) | 8.6 (6.6, 10.9) | 100.0 (99.9, 100.0) | 0.15 | 6.7 | |
B or D | 50 | 37 | 10 | 10,099 | 83.3 (71.5, 91.7) | 99.6 (99.5, 99.7) | 57.5 (46.4, 68.0) | 99.9 (99.8, 100.0) | 0.68 | 0.9 | |
Age < 20 years | |||||||||||
Ratio of type 1 to type 2 codes ≥ 0.5 (A) | 23 | 9 | 0 | 26 | 100.0 (85.2, 100.0) | 74.3 (56.7, 87.5) | 71.9 (53.3, 86.3) | 100.0 (86.8, 100.0) | 0.70 | 55.2 | 39.7 |
Ratio of type 1 to type 2 codes ≥ 4 (B) | 21 | 5 | 2 | 30 | 91.3 (72.0, 98.9) | 85.7 (69.7, 95.2) | 80.8 (60.6, 93.4) | 93.8 (79.2, 99.2) | 0.75 | 44.8 | |
At least 1 insulin prescription within 90 days (C) | 23 | 13 | 0 | 22 | 100.0 (85.2, 100.0) | 62.9 (44.9, 78.5) | 63.9 (46.2, 79.2) | 100.0 (84.6, 100.0) | 0.57 | 62.1 | |
Multiple daily injections with no other glucose-lowering medication prescription (D) | 16 | 3 | 7 | 32 | 69.6 (47.1, 86.8) | 91.4 (76.9, 98.2) | 84.2 (60.4, 96.6) | 82.1 (66.5, 92.5) | 0.63 | 32.8 | |
A and C | 23 | 8 | 0 | 27 | 100.0 (85.2, 100.0) | 77.1 (59.9, 89.6) | 74.2 (55.4, 88.1) | 100.0 (87.2, 100.0) | 0.73 | 53.4 | |
A and D | 16 | 2 | 7 | 33 | 69.6 (47.1, 86.8) | 94.3 (80.8, 99.3) | 88.9 (65.3, 98.6) | 82.5 (67.2, 92.7) | 0.66 | 31.0 | |
B and C | 21 | 5 | 2 | 30 | 91.3 (72.0, 98.9) | 85.7 (69.7, 95.2) | 80.8 (60.6, 93.4) | 93.8 (79.2, 99.2) | 0.75 | 44.8 | |
B and D | 15 | 2 | 8 | 33 | 65.2 (42.7, 83.6) | 94.3 (80.8, 99.3) | 88.2 (63.6, 98.5) | 80.5 (65.1, 91.2) | 0.62 | 29.3 | |
A or C | 23 | 14 | 0 | 21 | 100.0 (85.2, 100.0) | 60.0 (42.1, 76.1) | 62.2 (44.8, 77.5) | 100.0 (83.9, 100.0) | 0.54 | 63.8 | |
A or D | 23 | 10 | 0 | 25 | 100.0 (85.2, 100.0) | 71.4 (53.7, 85.4) | 69.7 (51.3, 84.4) | 100.0 (86.3, 100.0) | 0.66 | 56.9 | |
B or C | 23 | 13 | 0 | 22 | 100.0 (85.2, 100.0) | 62.9 (44.9, 78.5) | 63.9 (46.2, 79.2) | 100.0 (84.6, 100.0) | 0.57 | 62.1 | |
B or D | 22 | 6 | 1 | 29 | 95.7 (78.1, 99.9) | 82.9 (66.4, 93.4) | 78.6 (59.0, 91.7) | 96.7 (82.8, 99.9) | 0.76 | 48.3 | |
Age 20–39 years | |||||||||||
Ratio of type 1 to type 2 codes ≥ 0.5 (A) | 21 | 53 | 5 | 700 | 80.8 (60.6, 93.4) | 93.0 (90.9, 94.7) | 28.4 (18.5, 40.1) | 99.3 (98.4, 99.8) | 0.39 | 9.5 | 3.3 |
Ratio of type 1 to type 2 codes ≥ 4 (B) | 19 | 16 | 7 | 737 | 73.1 (52.2, 88.4) | 97.9 (96.6, 98.8) | 54.3 (36.6, 71.2) | 99.1 (98.1, 99.6) | 0.61 | 4.5 | |
At least 1 insulin prescription within 90 days (C) | 25 | 80 | 1 | 673 | 96.2 (80.4, 99.9) | 89.4 (87.0, 91.5) | 23.8 (16.0, 33.1) | 99.9 (99.2, 100.0) | 0.35 | 13.5 | |
Multiple daily injections with no other glucose-lowering medication prescription (D) | 13 | 3 | 13 | 750 | 50.0 (29.9, 70.1) | 99.6 (98.8, 99.9) | 81.3 (54.4, 96.0) | 98.3 (97.1, 99.1) | 0.61 | 2.1 | |
A and C | 20 | 23 | 6 | 730 | 76.9 (56.4, 91.0) | 96.9 (95.5, 98.1) | 46.5 (31.2, 62.3) | 99.2 (98.2, 99.7) | 0.56 | 5.5 | |
A and D | 10 | 1 | 16 | 752 | 38.5 (20.2, 59.4) | 99.9 (99.3, 100.0) | 90.9 (58.7, 99.8) | 97.9 (96.6, 98.8) | 0.53 | 1.4 | |
B and C | 18 | 8 | 8 | 745 | 69.2 (48.2, 85.7) | 98.9 (97.9, 99.5) | 69.2 (48.2, 85.7) | 98.9 (97.9, 99.5) | 0.68 | 3.3 | |
B and D | 10 | 1 | 16 | 752 | 38.5 (20.2, 59.4) | 99.9 (99.3, 100.0) | 90.9 (58.7, 99.8) | 97.9 (96.6, 98.8) | 0.53 | 1.4 | |
A or C | 26 | 110 | 0 | 643 | 100.0 (86.8, 100.0) | 85.4 (82.7, 87.8) | 19.1 (12.9, 26.7) | 100.0 (99.4, 100.0) | 0.28 | 17.5 | |
A or D | 24 | 55 | 2 | 698 | 92.3 (74.9, 99.1) | 92.7 (90.6, 94.5) | 30.4 (20.5, 41.8) | 99.7 (99.0, 100.0) | 0.43 | 10.1 | |
B or C | 26 | 88 | 0 | 665 | 100.0 (86.8, 100.0) | 88.3 (85.8, 90.5) | 22.8 (15.5, 31.6) | 100.0 (99.4, 100.0) | 0.34 | 14.6 | |
B or D | 22 | 18 | 4 | 735 | 84.6 (65.1, 95.6) | 97.6 (96.2, 98.6) | 55.0 (38.5, 70.7) | 99.5 (98.6, 99.9) | 0.65 | 5.1 | |
Age ≥ 40 years | |||||||||||
Ratio of type 1 to type 2 codes ≥ 0.5 (A) | 6 | 35 | 5 | 9313 | 54.5 (23.4, 83.3) | 99.6 (99.5, 99.7) | 14.6 (5.6, 29.2) | 99.9 (99.9, 100.0) | 0.23 | 0.4 | 0.1 |
Ratio of type 1 to type 2 codes ≥ 4 (B) | 3 | 11 | 8 | 9337 | 27.3 (6.0, 61.0) | 99.9 (99.8, 99.9) | 21.4 (4.7, 50.8) | 99.9 (99.8, 100.0) | 0.24 | 0.1 | |
At least 1 insulin prescription within 90 days (C) | 10 | 522 | 1 | 8826 | 90.9 (58.7, 99.8) | 94.4 (93.9, 94.9) | 1.9 (0.9, 3.4) | 100.0 (99.9, 100.0) | 0.03 | 5.7 | |
Multiple daily injections with no other glucose-lowering medication prescription (D) | 3 | 3 | 8 | 9345 | 27.3 (6.0, 61.0) | 100.0 (99.9, 100.0) | 50.0 (11.8, 88.2) | 99.9 (99.8, 100.0) | 0.35 | 0.1 | |
A and C | 6 | 21 | 5 | 9327 | 54.5 (23.4, 83.3) | 99.8 (99.7, 99.9) | 22.2 (8.6, 42.3) | 99.9 (99.9, 100.0) | 0.31 | 0.3 | |
A and D | 2 | 2 | 9 | 9346 | 18.2 (2.3, 51.8) | 100.0 (99.9, 100.0) | 50.0 (6.8, 93.2) | 99.9 (99.8, 100.0) | 0.27 | 0.0 | |
B and C | 3 | 6 | 8 | 9342 | 27.3 (6.0, 61.0) | 99.9 (99.9, 100.0) | 33.3 (7.5, 70.1) | 99.9 (99.8, 100.0) | 0.30 | 0.1 | |
B and D | 0 | 1 | 11 | 9347 | 0.0 (0.0, 28.5) | 100.0 (99.9, 100.0) | Undefined | 99.9 (99.8, 99.9) | 0.00 | 0.0 | |
A or C | 10 | 536 | 1 | 8812 | 90.9 (58.7, 99.8) | 94.3 (93.8, 94.7) | 1.8 (0.9, 3.3) | 100.0 (99.9, 100.0) | 0.03 | 5.8 | |
A or D | 7 | 36 | 4 | 9312 | 63.6 (30.8, 89.1) | 99.6 (99.5, 99.7) | 16.3 (6.8, 30.7) | 100.0 (99.9, 100.0) | 0.26 | 0.5 | |
B or C | 10 | 527 | 1 | 8821 | 90.9 (58.7, 99.8) | 94.4 (93.9, 94.8) | 1.9 (0.9, 3.4) | 100.0 (99.9, 100.0) | 0.03 | 5.7 | |
B or D | 6 | 13 | 5 | 9335 | 54.5 (23.4, 83.3) | 99.9 (99.8, 99.9) | 31.6 (12.6, 56.6) | 99.9 (99.9, 100.0) | 0.40 | 0.2 |