Table 4 Summary data for the 17 immune cell traits in the MESA case-cohort study

Pro-inflammatory cells

T helper type 1 (Th1) cells

770

15.3

9.0

0.0

65.5

T helper type 17 (Th17) cells

770

2.1

1.4

0.0

15.7

Activated CD4+ cells

1051

26.1

12.1

4.1

77.0

Activated CD8+ cells

1062

23.6

12.2

2.2

71.8

Natural Killer (NK) cells

1087

5.0

5.7

0.0

33.7

gamma delta T cells

1087

6.6

6.1

0.3

57.7

Classic Monocytes

922

74.4

10.2

9.3

96.3

Pro-fibrotic cells

T helper type 2 (Th2) cells

770

2.9

1.7

0.0

11.9

Non-classic Monocytes

922

7.4

7.5

0.0

81.4

Anti-inflammatory and anti-fibrotic cells

T regulatory cells (T-reg)

1035

5.0

2.2

0.0

15.2

Intermediate Monocytes

922

18.1

7.1

3.0

46.0

Pro-inflammatory cells that mark chronic use of adaptive immunity

Naive CD4+ cells

1051

26.1

12.0

1.6

70.8

Naive CD8+ cells

1062

52.4

14.7

6.5

97.1

Senescent CD4+ cells

1051

13.9

10.0

1.0

69.1

Senescent CD8+ cells

1062

55.6

15.9

10.4

94.0

CD4+ memory cells

1051

51.7

13.4

12.8

86.7

CD8+ memory cells

1062

21.7

10.6

0.0

79.2