Table 4 Personal factors and mean willingness-to-participate scores
Personal factors influencing the willingness to participate | Strongly agreed | Agreed | Indifferent | Disagreed | Strongly disagreed | P value* |
|---|---|---|---|---|---|---|
I could receive better treatment. N (%) | 65 (18.5%) | 182 (51.9%) | 52 (14.8%) | 34 (9.7%) | 18 (5.1%) | |
Mean score ± SD | 69.6 ± 19.0 | 60.9 ± 17.6 | 58.7 ± 18.3 | 56.8 ± 21.3 | 50.7 ± 24.5 | < 0.001 |
I could help other patients. N (%) | 110 (32.5%) | 179 (52.8%) | 33 (9.7%) | 13 (3.8%) | 4 (1.2%) | |
Mean score ± SD | 67.8 ± 17.4 | 60.3 ± 17.9 | 52.5 ± 21.3 | 44.9 ± 19.4 | 40.6 ± 18.8 | < 0.001 |
I could contribute to medical progress. N (%) | 147 (42.0%) | 172 (49.1%) | 23 (6.6%) | 6 (1.7%) | 2 (0.6%) | |
Mean score ± SD | 68.9 ± 16.3 | 57.4 ± 18.3 | 51.4 ± 22.0 | 45.8 ± 19.7 | 33.3 ± 11.8 | < 0.001 |
I would be considered a “guinea pig.” N (%) | 34 (9.8%) | 100 (28.9%) | 100 (28.9%) | 55 (15.9%) | 57 (16.5%) | |
Mean score ± SD | 50.1 ± 24.1 | 56.4 ± 18.0 | 63.7 ± 16.9 | 62.5 ± 15.4 | 70.5 ± 20.3 | < 0.001 |
I trust doctors. N (%) | 83 (23.2%) | 204 (57.0%) | 40 (11.2%) | 25 (7.0%) | 6 (1.7%) | |
Mean score ± SD | 68.2 ± 18.4 | 60.7 ± 17.0 | 54.7 ± 17.1 | 51.7 ± 23.8 | 41.0 ± 28.6 | < 0.001 |
I am afraid of adverse events related to the drug tested. N (%) | 82 (23.3%) | 155 (44.0%) | 52 (14.8%) | 47 (13.4%) | 16 (4.6%) | |
Mean score ± SD | 48.5 ± 20.8 | 58.2 ± 16.7 | 70.1 ± 16.5 | 69.8 ± 14.7 | 72.6 ± 26.9 | < 0.001 |
I could receive a more effective treatment. N (%) | 62 (18.7%) | 159 (47.9%) | 57 (17.2%) | 42 (12.7%) | 12 (3.6%) | |
Mean score ± SD | 70.1 ± 16.9 | 62.7 ± 16.1 | 56.9 ± 20.2 | 53.8 ± 18.5 | 54.5 ± 29.8 | < 0.001 |
I would respect my personal convictions. N (%) | 84 (25.5%) | 126 (38.3%) | 100 (30.4%) | 12 (3.7%) | 7 (2.1%) | |
Mean score ± SD | 65.6 ± 18.9 | 62.8 ± 15.7 | 59.5 ± 19.9 | 49.7 ± 19.2 | 46.4 ± 28.4 | < 0.001 |
I would be anxious about surgery. N (%) | 60 (17.0%) | 130 (36.8%) | 68 (19.3%) | 63 (17.9%) | 32 (9.1%) | |
Mean score ± SD | 52.4 ± 24.1 | 56.7 ± 18.0 | 64.2 ± 16.8 | 64.1 ± 14.9 | 76.5 ± 18.0 | < 0.001 |
I would be worried about inefficacy of the drug tested. N (%) | 48 (14.1%) | 119 (35.0%) | 73 (21.5%) | 76 (22.4%) | 24 (7.1%) | |
Mean score ± SD | 47.9 ± 25.3 | 57.2 ± 16.6 | 61.6 ± 16.5 | 66.8 ± 18.1 | 80.5 ± 17.3 | < 0.001 |
I think that research only benefits the doctor’s career. N (%) | 12 (3.5%) | 29 (8.3%) | 38 (10.9%) | 125 (35.9%) | 144 (41.4%) | |
Mean score ± SD | 38.9 ± 29.0 | 55.7 ± 14.8 | 57.0 ± 12.9 | 59.3 ± 17.7 | 65.9 ± 19.5 | < 0.001 |