Study-related factors influencing the willingness to participate | Strongly agreed | Agreed | No opinion | Disagreed | Strongly disagreed | P value* |
---|---|---|---|---|---|---|
If you received financial compensation, would you be more willing to participate? N (%) | 55 (14.9%) | 62 (16.8%) | 70 (18.9%) | 73 (19.7%) | 110 (29.7%) | |
Mean score ± SD | 65.5 ± 17.6 | 62.2 ± 15.8 | 63.1 ± 16.2 | 56.2 ± 18.8 | 57.3 ± 23.6 | 0.006 |
If participating in the study required commuting to the hospital, would you decline to participate? N (%) | 40 (11.1%) | 79 (21.9%) | 57 (15.8%) | 111 (30.8%) | 74 (20.5%) | |
Mean score ± SD | 48.3 ± 25.2 | 56.6 ± 17.3 | 60.8 ± 17.8 | 62.3 ± 15.5 | 69.1 ± 19.6 | < 0.001 |
If the study required blood tests, would you decline to participate? N (%) | 24 (6.4%) | 46 (12.3%) | 52 (13.9%) | 110 (29.4%) | 142 (38.0%) | |
Mean score ± SD | 44.3 ± 21.5 | 55.5 ± 17.7 | 55.4 ± 19.2 | 58.6 ± 15.1 | 68.2 ± 19.1 | < 0.001 |
If the study required randomly assigned treatment, would you decline to participate? N (%) | 95 (27.1%) | 110 (31.4%) | 42 (12.0%) | 76 (21.7%) | 27 (7.7%) | |
Mean score ± SD | 50.4 ± 22.6 | 58.6 ± 15.2 | 64.4 ± 16.4 | 66.1 ± 16.4 | 69.1 ± 24.4 | < 0.001 |
If the study required a treatment that was prescribed by the study and not by your doctor, would you be willing to participate? N (%) | 37 (10.4%) | 143 (40.1%) | 39 (10.9%) | 84 (23.5%) | 54 (15.1%) | |
Mean score ± SD | 71.1 ± 21.6 | 64.9 ± 13.3 | 59.5 ± 15.5 | 54.4 ± 19.3 | 48.4 ± 26.5 | < 0.001 |
If the study involved a placebo (inactive substance), would you decline to participate? N (%) | 40 (11.3%) | 62 (17.5%) | 65 (18.3%) | 101 (28.5%) | 87 (24.5%) | |
Mean score ± SD | 43.2 ± 27.8 | 56.7 ± 18.0 | 60.6 ± 17.3 | 61.2 ± 15.9 | 68.5 ± 17.2 | < 0.001 |
Many clinical trials are double-blind studies. This means that neither doctors nor the participants are aware which participants receive the test drug and which receive the placebo. Would you consider this a reason to decline participation? N (%) | 62 (17.5%) | 95 (26.8%) | 34 (9.6%) | 82 (23.2%) | 81 (22.9%) | |
Mean score ± SD | 48.5 ± 23.8 | 54.5 ± 16.6 | 64.9 ± 12.2 | 64.8 ± 16.0 | 70.4 ± 19.1 | < 0.001 |