Table 6 Multivariable logistic-regression model predicting willingness to participate
Willingness to participate in a clinical trial Beta coefficient | 95% Confidence interval | P value | |
|---|---|---|---|
Intercept (alpha) | 30.2 | 13.3 to 47.1 | 0.001 |
I am afraid of adverse events related to the drug tested (yes/ no) | −11.7 | −16.9 to −6.5 | < 0.001 |
I could help other patients. (yes/ no) | 9.6 | 3.4 to 15.7 | 0.002 |
I would not consider double-blinding a reason to decline participation. (yes/ no) | 5.7 | 1.3 to 10.2 | 0.012 |
I would be anxious about surgery. | −5.2 | −10.0 to −0.5 | 0.031 |
I could contribute to medical progress. (yes/ no) | 9.5 | 2.1 to 17.0 | 0.012 |
I could receive a more effective treatment. (yes/ no) | 4.7 | 0.2 to 9.2 | 0.041 |