Using estimated probability of pre-diagnosis behavior as a predictor of cancer survival time: an example in esophageal cancer

Table 2 Association Between Survival Time and Probability of Pre-Diagnosis Health Behavior; Esophageal Squamous Cell Carcinomas

Health behavior	1 year lag, unadjusted			1 year lag, adjusted^b			10 year lag, adjusted^b
Health behavior	HR^a	95% CI	P value	HR^a	95% CI	P value	HR^a	95% CI	P value
Current smoker	0.99	0.97,1.01	0.215	1.20	1.17,1.23	< 0.001	1.19	1.16,1.22	< 0.001
Alcohol - Heavy drinking	0.50	0.45,0.56	< 0.001	0.78	0.69,0.88	< 0.001	1.30	1.08,1.57	0.007
Alcohol - Binge drinking	0.75	0.73,0.78	< 0.001	0.95	0.90,1.00	0.035	1.09	1.02,1.17	0.013
Current smoker and ≥ 1 alcoholic drink /day	0.85	0.79,0.93	< 0.001	1.93	1.72,2.16	< 0.001	1.68	1.51,1.88	< 0.001
Did exercise in past 30 days other than regular job	0.78	0.76,0.79	< 0.001	0.82	0.80,0.85	< 0.001	0.79	0.77,0.82	< 0.001
Obese	0.97	0.94,0.99	0.004	1.07	1.04,1.10	< 0.001	1.08	1.04,1.11	< 0.001

Abbreviations: CI Confidence interval, HR Hazard ratio
^aThe hazard ratio describes the impact of a 0.1 increase in the probability of having the specified health behavior
^bAdjusted for age and cancer stage at diagnosis

ISSN: 1471-2288