Using estimated probability of pre-diagnosis behavior as a predictor of cancer survival time: an example in esophageal cancer

Table 3 Association Between Survival Time and Probability of Pre-Diagnosis Health Behavior; Esophageal Adenocarcinomas

	1 year lag, unadjusted			1 year lag, adjusted^b			10 year lag, adjusted^b
Health behavior	HR^a	95% CI	P value	HR^a	95% CI	P value	HR^a	95% CI	P value
Current smoker	1.00	0.98,1.01	0.625	1.20	1.18,1.23	< 0.001	1.18	1.16,1.21	< 0.001
Alcohol - Heavy drinking	0.55	0.51,0.59	< 0.001	0.85	0.77,0.93	< 0.001	1.10	0.95,1.26	0.216
Alcohol - Binge drinking	0.76	0.74,0.78	< 0.001	0.97	0.93,1.01	0.121	1.01	0.96,1.07	0.722
Current smoker and ≥ 1 alcoholic drink /day	0.89	0.83,0.95	< 0.001	1.93	1.76,2.11	< 0.001	1.79	1.65,1.94	< 0.001
Did exercise in past 30 days other than regular job	0.78	0.77,0.80	< 0.001	0.82	0.81,0.84	< 0.001	0.83	0.81,0.85	< 0.001
Obese	0.94	0.92,0.96	< 0.001	1.03	1.00,1.05	0.028	1.07	1.04,1.10	< 0.001

Abbreviations: CI Confidence interval, HR Hazard ratio
^aThe hazard ratio describes the impact of a 0.1 increase in the probability of having the specified health behavior
^bAdjusted for age and cancer stage at diagnosis

ISSN: 1471-2288