Table 2 Pooled Summary Estimates
Self-Reported Scale/Measure | Scale Abbreviation | Pooled Alpha; 95%CI | Pooled Kappa; 95%CI | Pooled Sensitivity; 95%CI | Pooled Specificity; 95%CI | Pooled PPV; 95%CI | Pooled NPV; 95%CI | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Alcohol Dependence Scale | ADS | 0.897 | 0.800 | – | 0.993 | ID |  | – |  | 0.908 | 0.822 | – | 0.955 | 0.794 | 0.671 | – | 0.879 | ID |  | – |  | ID |  | – |  |
Addiction Severity Index | ASI | 0.837 | 0.809 | – | 0.866 | ID |  | – |  | ID |  | – |  | ID |  | – |  | ID |  | – |  | ID |  | – |  |
Addiction Severity Index-Alcohol (alcohol sub-scale) | ASI-A | 0.773 | 0.732 | – | 0.814 | ID |  | – |  | 0.833 | 0.670 | – | 0.924 | 0.792 | 0.670 | – | 0.877 | ID |  | – |  | ID |  | – |  |
Addiction Severity Index-Drugs (drugs sub-scale) | ASI-D | 0.684 | 0.627 | – | 0.742 | ID |  | – |  | 0.839 | 0.753 | – | 0.899 | 0.854 | 0.766 | – | 0.913 | ID |  | – |  | ID |  | – |  |
The Alcohol, Smoking, and Substance Involvement Screening Test | ASSIST | 0.854 | 0.804 | – | 0.905 | ID |  | – |  | 0.834 | 0.799 | – | 0.868 | 0.726 | 0.570 | – | 0.882 | ID |  | – |  | ID |  | – |  |
Alcohol Use Disorders Identification Test | AUDIT | 0.847 | 0.829 | – | 0.865 | 0.461 | 0.253 | – | 0.669 | 0.860 | 0.838 | – | 0.879 | 0.872 | 0.854 | – | 0.888 | 0.610 | 0.510 | – | 0.710 | 0.940 | 0.927 | – | 0.953 |
Alcohol Use Disorders Identification Test-3 | AUDIT-3 | NA |  | – |  | ID |  | – |  | 0.844 | 0.800 | – | 0.879 | 0.835 | 0.750 | – | 0.895 | 0.631 | 0.491 | – | 0.771 | 0.940 | 0.902 | – | 0.979 |
Alcohol Use Disorders Identification Test-C | AUDIT-C | 0.748 | 0.695 | – | 0.802 | 0.410 | 0.386 | – | 0.433 | 0.874 | 0.843 | – | 0.900 | 0.842 | 0.811 | – | 0.870 | 0.496 | 0.390 | – | 0.602 | 0.878 | 0.834 | – | 0.923 |
Brief Michigan Alcoholism Screening Test | B-MAST | ID |  | – |  | ID |  | – |  | 0.502 | 0.381 | – | 0.622 | 0.971 | 0.956 | – | 0.981 | 0.653 | 0.376 | – | 0.930 | 0.902 | 0.866 | – | 0.937 |
Cut down, Annoyed, Guilty, Eye-opener | CAGE | 0.698 | 0.650 | – | 0.747 | 0.574 | 0.337 | – | 0.811 | 0.705 | 0.664 | – | 0.742 | 0.898 | 0.882 | – | 0.913 | 0.513 | 0.446 | – | 0.581 | 0.907 | 0.881 | – | 0.932 |
Composite International Diagnostic Interview, original | CIDI | NA |  | – |  | 0.815 | 0.610 | – | 1.020 | ID |  |  |  | ID |  |  |  | ID |  |  |  | ID |  |  |  |
Composite International Diagnostic Interview,version 2.1 | CIDI, version 2.1 | NA |  |  |  | ID |  |  |  | 0.749 | 0.686 | – | 0.812 | 0.842 | 0.689 | – | 0.995 | ID |  |  |  | ID |  |  |  |
Composite International Diagnostic Interview, version 3 | CIDI, version 3 | NA |  |  |  | ID |  |  |  | 0.913 | 0.816 | – | 1.010 | 0.990 | 0.985 | – | 0.995 | 0.914 | 0.871 | – | 0.958 | 0.990 | 0.985 | – | 0.995 |
Car, Relax, Alone, Forget, Friends, Trouble | CRAFFT | 0.687 | 0.639 | – | 0.735 | ID |  | – |  | 0.897 | 0.837 | – | 0.937 | 0.764 | 0.675 | – | 0.834 | 0.571 | 0.343 | – | 0.799 | 0.857 | 0.449 | – | 1.00 |
Drug Abuse Screen Test | DAST | 0.937 | 0.927 | – | 0.947 | 0.832 | 0.577 | – | 1.0 | 0.847 | 0.740 | – | 0.915 | 0.844 | 0.679 | – | 0.932 | 0.510 | 0.323 | – | 0.698 | 0.946 | 0.892 | – | 0.999 |
Drug Abuse Screen Test - 10 item | DAST-10 | 0.785 | 0.678 | – | 0.892 | ID |  | – |  | 0.902 | 0.748 | – | 0.966 | 0.81 8 | 0.716 | – | 0.889 | 0.803 | 0.695 | – | 0.910 | 0.864 | 0.813 | – | 0.914 |
Drug Use Disorders Identification Test | DUDIT | 0.922 | 0.895 | – | 0.950 | ID |  | – |  | 0.932 | 0.887 | – | 0.960 | 0.789 | 0.672 | – | 0.872 | 0.606 | 0.342 | – | 0.869 | 0.915 | 0.822 | – | 1.00 |
Michigan Alcohol Screening Test | MAST | 0.822 | 0.780 | – | 0.863 | 0.693 | 0.578 | – | 0.808 | 0.705 | 0.583 | – | 0.804 | 0.853 | 0.774 | – | 0.908 | 0.507 | 0.302 | – | 0.713 | 0.878 | 0.816 | – | 0.940 |
Problem Oriented Screening Instrument for Teenagers | POSIT | 0.857 | 0.730 | – | 0.984 | 0.881 | 0.817 | – | 0.945 | 0.842 | 0.722 | – | 0.962 | 0.823 | 0.745 | – | 0.902 | ID |  | – |  | ID |  | – |  |
Self-Administered Alcoholism Screening Test | SAAST | 0.889 | 0.791 | – | 0.987 | ID |  | – |  | 0.522 | 0.331 | – | 0.714 | 0.825 | 0.755 | – | 0.896 | 0.320 | 0.219 | – | 0.422 | 0.917 | 0.890 | – | 0.945 |
Semi-Structured Assessment for Drug Dependence and Alcoholism | SSADDA | ID |  | – |  | 0.837 | 0.767 | – | 0.907 | ID |  | – |  | ID |  | – |  | ID |  | – |  | ID |  | – |  |
Severity of Dependence | SDS | 0.855 | 0.780 | – | 0.931 | ID |  | – |  | 0.830 | 0.759 | – | 0.901 | 0.837 | 0.782 | – | 0.892 | 0.897 | 0.856 | – | 0.937 | 0.826 | 0.761 | – | 0.891 |
Tolerance-Annoyance Cut Down Eye Opener | TACE | 0.495 | 0.466 | – | 0.524 | ID |  | – |  | 0.827 | 0.737 | – | 0.918 | 0.722 | 0.651 | – | 0.793 | 0.349 | 0.245 | – | 0.453 | 0.867 | 0.622 | – | 1.0 |
Timeline Followback | TLFB | NA |  | – |  | 0.857 | 0.807 | – | 0.907 | 0.798 | 0.725 | – | 0.872 | 0.965 | 0.945 | – | 0.986 | ID |  | – |  | ID |  | – |  |
Tolerance, Worried, Eye-Opener, Amnesia, Cut down | TWEAK | 0.619 | 0.551 | – | 0.688 | ID |  | – |  | 0.850 | 0.797 | – | 0.890 | 0.864 | 0.820 | – | 0.898 | 0.434 | 0.263 | – | 0.606 | 0.880 | 0.704 | – | 1.0 |
The Chemical Use, Abuse, and Dependence | CUAD | 0.962 | 0.940 | – | 0.983 | ID |  | – |  | ID |  | – |  | ID |  | – |  | ID |  | – |  | ID |  | – |  |
Biomarkers | Abbreviation | Pooled Alpha; 95%CI | Pooled Kappa; 95%CI | Pooled Sensitivity; 95%CI | Pooled Specificity; 95%CI | Pooled PPV; 95%CI | Pooled NPV; 95%CI | ||||||||||||||||||
% Carbohydrate deficient transferrin | %CDT | NA |  |  |  | NA |  | – |  | 0.565 | 0.471 | – | 0.654 | 0.913 | 0.884 | – | 0.936 | 0.580 | 0.377 | – | 0.783 | 0.850 | 0.782 | – | 0.918 |
Alanine transaminase | ALT | NA |  | – |  | NA |  | – |  | 0.316 | 0.239 | – | 0.403 | 0.882 | 0.830 | – | 0.920 | 0.372 | 0.183 | – | 0.560 | 0.632 | 0.417 | – | 0.846 |
Aspartate transaminase | AST | NA |  | – |  | NA |  | – |  | 0.476 | 0.400 | – | 0.552 | 0.865 | 0.814 | – | 0.903 | 0.420 | 0.273 | – | 0.567 | 0.693 | 0.554 | – | 0.833 |
Aspartate transaminase, Alanine transaminase ratio | AST/ALT | NA |  | – |  | NA |  | – |  | 0.340 | 0.220 | – | 0.460 | 0.728 | 0.519 | – | 0.937 | ID |  | – |  | ID |  | – |  |
Blood alcohol concentration | BAC | NA |  | – |  | NA |  | – |  | 0.638 | 0.589 | – | 0.686 | 0.795 | 0.719 | – | 0.871 | 0.596 | 0.145 | – | 1.0 | 0.687 | 0.518 | – | 0.856 |
Carbohydrate deficient transferrin | CDT | NA |  | – |  | NA |  | – |  | 0.585 | 0.425 | – | 0.728 | 0.959 | 0.932 | – | 0.976 | 0.853 | 0.740 | – | 0.966 | 0.790 | 0.727 | – | 0.854 |
CDTech | CDTech | NA |  | – |  | NA |  | – |  | 0.537 | 0.450 | – | 0.622 | 0.895 | 0.876 | – | 0.911 | 0.518 | 0.367 | – | 0.669 | 0.795 | 0.614 | – | 0.975 |
Carbohydrate deficient transferrin + Mean corpuscular volume | CDT + MCV | NA |  | – |  | NA |  | – |  | 0.742 | 0.599 | – | 0.884 | 0.928 | 0.908 | – | 0.947 | 0.741 | 0.509 | – | 0.974 | 0.917 | 0.826 | – | 1.00 |
Gamma-Glutamyl Transferase | GGT | NA |  | – |  | NA |  | – |  | 0.571 | 0.502 | – | 0.638 | 0.827 | 0.782 | – | 0.865 | 0.430 | 0.351 | – | 0.509 | 0.819 | 0.701 | – | 0.937 |
Gamma-Glutamyl Transferase + Mean corpuscular volume | GGT + MCV | NA |  | – |  | NA |  | – |  | 0.641 | 0.377 | – | 0.840 | 0.870 | 0.759 | – | 0.935 | 0.470 | 0.275 | – | 0.664 | 0.880 | 0.813 | – | 0.948 |
Ethyl glucuronide | EtG | NA |  | – |  | NA |  | – |  | 0.825 | 0.606 | – | 0.936 | 0.953 | 0.896 | – | 0.979 | 0.614 | 0.389 | – | 0.840 | 0.857 | 0.779 | – | 0.935 |
Mean corpuscular volume | MCV | NA |  | – |  | NA |  | – |  | 0.390 | 0.330 | – | 0.453 | 0.905 | 0.878 | – | 0.927 | 0.476 | 0.362 | – | 0.589 | 0.794 | 0.728 | – | 0.860 |
Phosphatidylethanol | PEth | NA |  | – |  | NA |  | – |  | 0.871 | 0.787 | – | 0.956 | 0.939 | 0.905 | – | 0.973 | ID |  | – |  | ID |  | – |  |