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Table 3 Characteristics of analysed clinical trial registrations

From: Research methodology and characteristics of journal articles with original data, preprint articles and registered clinical trial protocols about COVID-19

Variable (N of trials with reported variable)N (%)a
Clinical trial registry (N = 927)
 Chinese Clinical Trials Registry (ChiCTR)581 (63)
ClinicalTrials.gov286 (30)
 EU Clinical Trials Register21 (2.2)
 Australian New Zealand Clinical Trials Registry (ANZCTR)9 (1)
 ISRCTN8 (0.9)
 IRCT8 (0.9)
 Other14 (1.5)
Recruitment status (N = 915)
 Not recruiting453 (50)
 Recruiting441 (48)
 Authorized21 (2.2)
Minimal age of participants (N = 744)
 18 years532 (72)
 0 years26 (3.5)
 14 years18 (2.4)
 16 years15 (2)
 1 year13 (1.7)
 Other140 (15)
Maximal age of participants (N = 663)
 Not applicable/no upper limit197 (30)
 80 years59 (9)
 75 years55 (8.2)
 90 years42 (6.3)
 65 years32 (4.8)
 Other278 (42)
Eligibility of participants based on sex (N = 921)
 Both men and women892 (97)
 Only men18 (1.9)
 Only women11 (1.2)
Self-reported study type (N = 927)
 Interventional535 (58)
 Observational303 (33)
 Diagnostic test35 (3.8)
 Observational (patient registry)19 (2)
 Epidemiological research10 (1)
 Other25 (2.7)
Location of trials located in single countries (N = 825)
 China622 (63)
 United States33 (4.0)
 France21 (2.5)
 Italy17 (2.1)
 United Kingdom10 (1.2)
 Other122 (15)
Tested interventions (N = 535)
 Hydroxychloroquine39 (7.2)
 Chloroquine16 (3.0)
 Tocilizumab10 (1.9)
 Lopinavir/ritonavir combination10 (1.9)
 Convalescent plasma9 (1.7)
 Other451 (84)
  1. aDenominator is provided in the first column, as “N of trials with reported variable”; for some variables due to rounding the sums may not be exact 100%, for variables we presented only five most frequent categories