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Table 3 Characteristics of analysed clinical trial registrations

From: Research methodology and characteristics of journal articles with original data, preprint articles and registered clinical trial protocols about COVID-19

Variable (N of trials with reported variable)

N (%)a

Clinical trial registry (N = 927)

 Chinese Clinical Trials Registry (ChiCTR)

581 (63)

ClinicalTrials.gov

286 (30)

 EU Clinical Trials Register

21 (2.2)

 Australian New Zealand Clinical Trials Registry (ANZCTR)

9 (1)

 ISRCTN

8 (0.9)

 IRCT

8 (0.9)

 Other

14 (1.5)

Recruitment status (N = 915)

 Not recruiting

453 (50)

 Recruiting

441 (48)

 Authorized

21 (2.2)

Minimal age of participants (N = 744)

 18 years

532 (72)

 0 years

26 (3.5)

 14 years

18 (2.4)

 16 years

15 (2)

 1 year

13 (1.7)

 Other

140 (15)

Maximal age of participants (N = 663)

 Not applicable/no upper limit

197 (30)

 80 years

59 (9)

 75 years

55 (8.2)

 90 years

42 (6.3)

 65 years

32 (4.8)

 Other

278 (42)

Eligibility of participants based on sex (N = 921)

 Both men and women

892 (97)

 Only men

18 (1.9)

 Only women

11 (1.2)

Self-reported study type (N = 927)

 Interventional

535 (58)

 Observational

303 (33)

 Diagnostic test

35 (3.8)

 Observational (patient registry)

19 (2)

 Epidemiological research

10 (1)

 Other

25 (2.7)

Location of trials located in single countries (N = 825)

 China

622 (63)

 United States

33 (4.0)

 France

21 (2.5)

 Italy

17 (2.1)

 United Kingdom

10 (1.2)

 Other

122 (15)

Tested interventions (N = 535)

 Hydroxychloroquine

39 (7.2)

 Chloroquine

16 (3.0)

 Tocilizumab

10 (1.9)

 Lopinavir/ritonavir combination

10 (1.9)

 Convalescent plasma

9 (1.7)

 Other

451 (84)

  1. aDenominator is provided in the first column, as “N of trials with reported variable”; for some variables due to rounding the sums may not be exact 100%, for variables we presented only five most frequent categories