Characteristic | REACH-HF n = 107 (%) | Qualitative interview sample n = 19 (%) |
---|---|---|
Age (years), mean (SD) | 69.7 (10.9) | 68.5 (9.8) |
Female sex | 26 (24) | 7 (37) |
BMI (kg/m2); mean (SD) | 29.5 (6.6) | 31.5 (7.4) |
Main activity | ||
 Retired | 81 (76) | 15 (79) |
 In employment or self-employment | 18 (17) | 2 (11) |
 Unemployed | 5 (5) | 1 (5) |
 Other | 3 (3) | 1 (5) |
Ethnic origin | ||
 White | 100 (93) | 19 (100) |
 Other (Black, Asian, other) | 7 (7) | 0 (0) |
NYHA status | ||
 Class I | 24 (22) | 0 (0) |
 Class II | 63 (59) | 13 (68) |
 Class III | 20 (19) | 6 (32) |
Ischaemic aetiology of HF | 48 (45) | 9 (47) |
Time since diagnosis of HF (years) | ||
  < 1 | 35 (33) | 6 (32) |
 1–2 | 18 (17) | 1 (5) |
  > 2 | 54 (51) | 12 (63) |
LVEF (%); mean (SD), n | 32 (8), 76 | 27 (9), 11 |
NT-pro-BNP level (pg/mL); mean (SD) | 1460 (1928) | 1321 (1123) |
Current smoker | 6 (6) | 1 (5) |
Comorbidities (past or present) | ||
 Diabetes mellitus | 26 (24) | 5 (26) |
 Myocardial infarction | 29 (27) | 7 (37) |
 Hypertension | 45 (42) | 9 (47) |
 Chronic renal impairment | 14 (13) | 3 (16) |
 Arthritis (osteoarthritis or rheumatoid) | 45 (42) | 11 (58) |
 Atrial fibrillation or atrial flutter | 48 (45) | 9 (47) |
 COPD | 9 (8) | 2 (11) |
 Depression | 27 (25) | 7 (37) |
Number of comorbidities | ||
 0 | 63 (59) | 9 (47) |
 1 | 32 (30) | 7 (37) |
 2 | 7 (7) | 1 (5) |
 3 | 5 (5) | 2 (11) |
Baseline use of drugs | ||
 Beta-blocker | 90 (84) | 18 (5) |
 Angiotensin II receptor antagonist | 31 (29) | 8 (42) |
 ACE inhibitor | 68 (64) | 10 (53) |
Baseline use of devices | ||
 ICD | 10 (9) | 3 (16) |
 CRT | 10 (9) | 1 (5) |
 Combined CRT/ICD | 5 (5) | 2 (11) |
 Pacemaker | 11 (10) | 1 (5) |
Location | ||
 Cornwall | 30 (28) | 7 (37) |
 Gwent | 23 (22) | 3 (16) |
 Birmingham | 27 (25) | 4 (21) |
 York | 27 (25) | 5 (26) |
Caregiver present at randomisation | 53 (50) | 13 (68) |