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Fig. 1 | BMC Medical Research Methodology

Fig. 1

From: Modeling adaptive response profiles in a vaccine clinical trial

Fig. 1

Time profiles of antibody (Ab) levels. Each Ab-profile (plotted in a different color from the gradient blue color scale) denotes a subject. The y-axis denotes the antibody levels on log10 scale. The x-axis indicates the measurement points: prior to vaccinations (PRE), Day 30 (PI(D30)), Day 44 (PII(D44)), Day 60 (PII(D60)), Day 180 (PII(D180)) and Day 360 (PII(D360)). PI and PII show the measurements after the first and second vaccinations, respectively. The five panels correspond to different adjuvants (AS01B, AS01E, AS03A, AS04 and Alum) and each group consists of different subjects. The bird’s eye view on Ab levels presented here helps to visualise the increased divergence between the individual responses observed especially in the AS04 and Alum groups

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