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Fig. 2 | BMC Medical Research Methodology

Fig. 2

From: Modeling adaptive response profiles in a vaccine clinical trial

Fig. 2

Population estimates for the 2-segment and 3-segment PW linear models with a-priori fixed knot locations. Black lines show the time profile (interconnected data points) of an individual. Red and blue lines (estimates interconnected at the measurement points) show the population estimates obtained by the 2-segment and 3-segment PW linear models with a-priori fixed knot locations. These 5 individuals are typical examples of their adjuvant group. Therefore, the population estimates obtained by the models (time profile prediction obtained by using only the fixed part of the model) should reflect the example individual time profile

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