Table 3 Information on comorbidities and prescription medications recorded for the linked sample. Column 1: information recorded in the CHHiP trial at baseline (pre-radiotherapy), Column 2: information in primary care before enrolment to the CHHiP trial and Column 5: information in primary care after enrolment to the CHHiP trial. Date of the trial enrolment was defined as the start date of androgen deprivation therapy. Columns 3 and 4: information not recorded in each of the databases respectively
| Â | Information recorded at baseline in the CHHiP trial n (%) | Information recorded in primary care before enrolment to CHHiP n (%) | Not recoded in the trial n (%) | Not recorded in primary care n (%) | Information recorded in primary care after enrolment to CHHiP n (%) (new diagnosis) |
|---|---|---|---|---|---|
Past clinical history of comorbidity | |||||
 Diabetes | 9 (8) | 11 (10) (type1–1, type2–10) | 2 (2) | 0 | 12 (11) (all participants type2) |
 Hypertension | 38 (36) | 40 (38) | 14 (13) | 12 (11) | 9 (8) |
 Inflammatory bowel disease | 2 (2) | Not extracted | – | – | – |
 Symptomatic haemorrhoids | 5 (5) | 5 (5) | 5 (5) | 5 (5) | 14 (13) |
Previous pelvic surgery / prostatectomy | 8 (7) | 14 (13) | 11 (10) | 5 (5) | 3 (3) |
Previous transurethral resection of the prostate | 16 (15) | 52 (49) | 38 (36) | 2 (2) | 3 (3) |
Medication | |||||
 Alpha-blocker or anticholinergic | 12 (11) | 9 (8) | 8 (7) | 11 (10) | 16 (15) |
 Angiotensin converting enzyme inhibitors | Not recorded | 22 (20) | 22 (21) | – | 15 (14) |
 Statins | Not recorded | 40 (38) | 40 (38) | – | 25 (24) |
 Metformin | Not recorded | 7 (7) | 7 (7) | – | 7 (7) |
 Aspirin | Not recorded | 32 (30) | 32 (30) | – | 12 (11) |
 Phosphodiesterase type 5 inhibitors | Not recorded | 20 (19) | 20 (19) | – | 26 (25) |
 Rectal steroids | Not recorded | 7 (7) | 7 (7) | – | 17 (16) |