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Fig. 1 | BMC Medical Research Methodology

Fig. 1

From: A new randomization procedure based on multiple covariates and applicable to parallel studies with simultaneous enrollment of all subjects prior to intervention

Fig. 1

D s-efficiencies for potential complete randomizations in the motivating example. Ten thousand study designs are generated by random allocation of subject to arms, not stratified by any covariate. The figure shows Ds efficiencies of the 10,000 study designs with respect to covariates gender, age, BMI, a composite health score and membership of one of 17 first-visit groups as covariates. The red bar denotes the efficiency obtained with the proposed procedure, which addresses all covariates simultaneously

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