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Fig. 4 | BMC Medical Research Methodology

Fig. 4

From: A non-linear optimisation method to extract summary statistics from Kaplan-Meier survival plots using the published P value

Fig. 4

Assessing how the weighting of points in a KM plot affects the estimation of ln (HR) and var. ln (HR). The KM plot from Fig. 2a was used to determine the effect of weighting points at different areas of the KM plot. The KM plot was split into three equally divided sectors along the entire timeframe of study (a). A total of thirty points was randomly distributed according to the weights described in Table 3. Representative images of this are presented in (b) with the vertical lines indicating the points chosen. c and d represent the mean and SD of ln (HR) and var. ln (HR) from 100 Monte Carlo simulations, respectively

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