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Table 1 The dosage and sample size for each dose-response arm within HOBIT trial

From: Two-stage Bayesian hierarchical modeling for blinded and unblinded safety monitoring in randomized clinical trials

Eight Arms

Dose (Oxygen Toxicity Units)

Sample Size

(N = 53)

1

Control (1.0 ATA)

0.0

11

2

1.5 ATA

2.60

6

3

2 ATA

4.17

6

4

NBH (100% FiO2 at 1.0 ATA)

5.40

6

5

2.5 ATA

5.92

6

6

1.5 ATA + NBH

6.20

6

7

2 ATA + NBH

7.76

6

8

2.5 ATA + NBH

9.52

6

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BMC Medical Research Methodology

ISSN: 1471-2288

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