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Fig. 3 | BMC Medical Research Methodology

Fig. 3

From: Handling informative dropout in longitudinal analysis of health-related quality of life: application of three approaches to data from the esophageal cancer clinical trial PRODIGE 5/ACCORD 17

Fig. 3

Predicted HRQoL score trajectories of the pattern-mixture model. Legend: Predictions over time by treatment arm regimen for the four dimensions of EORTC QLQ-C30 (QL, PF, PA, and FA). The linear trajectories are shown in pattern 1 (last measurement at visits V0 = 0, V1 = 1.25, or V2 = 3 months), pattern 2 (last measurement at visits V3 = 4 or V4 = 6 months), pattern 3 (last measurement at visits V5 = 12 months), pattern 4 (last measurement at visits V6 = 24 or V7 = 36 months, i.e., no dropout) and the overall patterns (marginal HRQoL scores). The solid line refers to the control fluorouracil-cisplatin regimen and the dashed line refers the experimental FOLFOX regimen

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