TY - JOUR AU - Wake, Melissa AU - Hu, Yanhong Jessika AU - Warren, Hayley AU - Danchin, Margie AU - Fahey, Michael AU - Orsini, Francesca AU - Pacilli, Maurizio AU - Perrett, Kirsten P. AU - Saffery, Richard AU - Davidson, Andrew PY - 2020 DA - 2020/09/24 TI - Integrating trials into a whole-population cohort of children and parents: statement of intent (trials) for the Generation Victoria (GenV) cohort JO - BMC Medical Research Methodology SP - 238 VL - 20 IS - 1 AB - Very large cohorts that span an entire population raise new prospects for the conduct of multiple trials that speed up advances in prevention or treatment while reducing participant, financial and regulatory burden. However, a review of literature reveals no blueprint to guide this systematically in practice. This Statement of Intent proposes how diverse trials may be integrated within or alongside Generation Victoria (GenV), a whole-of-state Australian birth cohort in planning, and delineates potential processes and opportunities. SN - 1471-2288 UR - https://doi.org/10.1186/s12874-020-01111-x DO - 10.1186/s12874-020-01111-x ID - Wake2020 ER -