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Table 1 Parameters used in the simulation of the A and B arms

From: Performance of unanchored matching-adjusted indirect comparison (MAIC) for the evidence synthesis of single-arm trials with time-to-event outcomes

  A arm B arm
Sample size 1000 800
Mean age 53 56
Standard deviation of age 11 12
Range of age [21, 80] [23, 85]
Menopausal status (% post-menopausal) 40 50
tumor grade = 1 (%) 20 10
tumor grade = 2 (%) 65 70
tumor grade = 3 (%) 15 20
Distribution Weibull Weibull
Scale parameter 0.00000004 0.00000004
Shape parameter 2.2 2.2
Coefficients of variables (logHR)   
Age (yearly increment) 0.02 0.02
Menopausal status 0.5 0.5
Indicator variable for tumor grade = 2 0.3 0.3
Indicator variable for tumor grade = 3 0.6 0.6
B indicator NA −0.5 (in the scenario without effect modifier) / -0.4 (in the scenario with effect modifier)
B indicator × menopausal status interaction NA −0.2 (only applicable to the scenario with effect modifier)
Maximum follow-up time (days) 2500 2500
  1. Abbreviation: HR Hazard ratio; NA Not applicable