| A arm | B arm |
---|---|---|
Sample size | 1000 | 800 |
Mean age | 53 | 56 |
Standard deviation of age | 11 | 12 |
Range of age | [21, 80] | [23, 85] |
Menopausal status (% post-menopausal) | 40 | 50 |
tumor grade = 1 (%) | 20 | 10 |
tumor grade = 2 (%) | 65 | 70 |
tumor grade = 3 (%) | 15 | 20 |
Distribution | Weibull | Weibull |
Scale parameter | 0.00000004 | 0.00000004 |
Shape parameter | 2.2 | 2.2 |
Coefficients of variables (logHR) | Â | Â |
Age (yearly increment) | 0.02 | 0.02 |
Menopausal status | 0.5 | 0.5 |
Indicator variable for tumor grade = 2 | 0.3 | 0.3 |
Indicator variable for tumor grade = 3 | 0.6 | 0.6 |
B indicator | NA | −0.5 (in the scenario without effect modifier) / -0.4 (in the scenario with effect modifier) |
B indicator × menopausal status interaction | NA | −0.2 (only applicable to the scenario with effect modifier) |
Maximum follow-up time (days) | 2500 | 2500 |