Skip to main content

Table 3 Estimated Changes in ln(CD4 +) and ln(Odds of Viral Load Suppression) per Year for Untreated Subjects in the WIHS Using the BNSV and GLMM Methods. Changes in ln(CD4 +) assume a baseline CD4 + of 478.5. Changes in ln(odds) assume baseline CD4 + of 267 and baseline log10(viral load)=4.2. PM=posterior mean, CI=credible interval, PP=posterior probability of a difference <0, indicating steeper declines in CD4 + and less rapid increases in odds of viral load suppression among drug users

From: A Bayesian natural cubic B-spline varying coefficient method for non-ignorable dropout

  Others Drug users Difference
  PM 95% CI PM 95% CI PM 95% CI PP
A) Untreated:Δ ln(CD4+)
BNSV -0.20 (-0.23, -0.16) -0.41 (-0.53, -0.29) -0.21 (-0.34,-0.09) 0.9996
Frailty Model -0.19 (-0.22, -0.15) -0.27 (-0.33, -0.22) -0.08 (-0.15, -0.02) 0.99
CLM -0.20 (-0.22, -0.17) -0.27 (-0.32, -0.22) -0.07 (-0.13, -0.02) 0.99
GLMM -0.16 (-0.18, -0.13) -0.24 (-0.29, -0.18) -0.08 (-0.14, -0.02) 0.99
B) HAART:
Δ ln(Odds of Suppression)
BNSV 0.11 (0.005, 0.17) 0.09 (-0.06, 0.25) -0.02 (-0.18,0.15) 0.61
Frailty Model 0.18 (0.14, 0.23) 0.15 (0.05, 0.25) -0.03 (-0.14, 0.07) 0.74
CLM 0.12 (0.06, 0.17) 0.08 (-0.04, 0.19) -0.04 (-0.16, 0.09) 0.73
GLMM 0.26 (0.22,0.29) 0.21 (0.14, 0.28) -0.05 (-0.13, 0.03) 0.90