Table 3 Estimated Changes in ln(CD4 +) and ln(Odds of Viral Load Suppression) per Year for Untreated Subjects in the WIHS Using the BNSV and GLMM Methods. Changes in ln(CD4 +) assume a baseline CD4 + of 478.5. Changes in ln(odds) assume baseline CD4 + of 267 and baseline log10(viral load)=4.2. PM=posterior mean, CI=credible interval, PP=posterior probability of a difference <0, indicating steeper declines in CD4 + and less rapid increases in odds of viral load suppression among drug users
From: A Bayesian natural cubic B-spline varying coefficient method for non-ignorable dropout
| Â | Others | Drug users | Difference | ||||
|---|---|---|---|---|---|---|---|
| Â | PM | 95% CI | PM | 95% CI | PM | 95% CI | PP |
A) Untreated:Δ ln(CD4+) | |||||||
BNSV | -0.20 | (-0.23, -0.16) | -0.41 | (-0.53, -0.29) | -0.21 | (-0.34,-0.09) | 0.9996 |
Frailty Model | -0.19 | (-0.22, -0.15) | -0.27 | (-0.33, -0.22) | -0.08 | (-0.15, -0.02) | 0.99 |
CLM | -0.20 | (-0.22, -0.17) | -0.27 | (-0.32, -0.22) | -0.07 | (-0.13, -0.02) | 0.99 |
GLMM | -0.16 | (-0.18, -0.13) | -0.24 | (-0.29, -0.18) | -0.08 | (-0.14, -0.02) | 0.99 |
B) HAART: | |||||||
Δ ln(Odds of Suppression) | |||||||
BNSV | 0.11 | (0.005, 0.17) | 0.09 | (-0.06, 0.25) | -0.02 | (-0.18,0.15) | 0.61 |
Frailty Model | 0.18 | (0.14, 0.23) | 0.15 | (0.05, 0.25) | -0.03 | (-0.14, 0.07) | 0.74 |
CLM | 0.12 | (0.06, 0.17) | 0.08 | (-0.04, 0.19) | -0.04 | (-0.16, 0.09) | 0.73 |
GLMM | 0.26 | (0.22,0.29) | 0.21 | (0.14, 0.28) | -0.05 | (-0.13, 0.03) | 0.90 |