Skip to main content

Table 4 EHR estimates with data on colorectal cancer using life tables stratified and not stratified by sex

From: Correcting inaccurate background mortality in excess hazard models through breakpoints

  Model 1* Model 1 Model 2 Model 3 (Ɛ1 = 83, Ɛ2 = 88)
Variables EHR [95% CI] EHR [95% CI] EHR [95% CI] \( \hat{\alpha} \)[95% CI] EHR [95% CI] \( \hat{\alpha} \)[95% CI]
Age
 ≤ 64 ref. ref. ref.   ref.  
 65–74 1.37 [1.01–1.87] 1.35 [1.00–1.82] 1.36 [1.00–1.85]   1.37 [1.01–1.87]  
 75–90 1.67 [1.21–2.31] 1.69 [1.23–2.33] 1.67 [1.16–2.40]   1.66 [1.15–2.38]  
CS
 I ref. ref. ref.   ref.  
 II 5.92 [2.35–14.90] 5.26 [2.32–11.88] 6.47 [1.82–22.95]   5.75 [1.66–19.91]  
 III-IV 14.65 [5.91–36.33] 12.57 [5.65–27.99] 16.07 [4.28–60.32]   14.31 [3.85–53.10]  
Sex
 Men ref. ref. ref. 1.33 [0.92–1.92] ref. 1.42 [0.90–2.24]a
      1.24 [0.74–2.07]b
      0.66 [0.32–1.39]c
 Women 0.93 [0.72–1.20] 0.69 [0.53–0.90] 0.91 [0.67–1.24] 0.74 [0.59–0.93] 0.94 [0.70–1.29] 0.62 [0.45–0.84]a
      0.77 [0.57–1.02]b
      1.74 [0.59–5.11]c
AIC 4223 4238 4230 4228
  1. Note: Model 1* (Gold standard) is estimated using a life table stratified by sex and Models 1, 2, and 3 are estimated using the same life table not stratified by sex. Excess hazard ratio (EHR) with 95% confidence interval (95% CI) are estimated for Models 1*,1,2 and 3, while α with 95% CI are estimated for Model 2 and 3. Ɛ1, Ɛ2, Determined breakpoints; CS, Cancer stage; a Estimate of α before Ɛ1; b Estimate of α between Ɛ1 and Ɛ2, c Estimate of α after Ɛ2; AIC, Akaike information criterion