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Table 5 EHR estimates with data on colorectal cancer using a life table not stratified by SPC

From: Correcting inaccurate background mortality in excess hazard models through breakpoints

 

Model 1

Model 2

Model 3 (Ɛ = 75)

Variables

EHR [95% CI]

EHR [95% CI]

\( \hat{\alpha} \)[95% CI]

EHR [95% CI]

\( \hat{\alpha} \)[95% CI]

Age

 ≤ 64

ref.

ref.

 

ref.

 

 65–74

1.69 [1.15–2.50]

1.70 [1.16–2.49]

 

1.74 [1.25–2.43]

 

 75–90

2.14 [1.43–3.18]

2.21 [1.43–3.42]

 

2.14 [1.41–3.24]

 

Sex

 Men

ref.

ref.

 

ref.

 

 Women

0.93 [0.65–1.33]

0.94 [0.63–1.38]

 

0.80 [0.53–1.21]

 

CS

 I

ref.

ref.

 

ref.

 

 II

3.71 [1.53–8.99]

2.94 [1.27–6.79]

 

2.91 [1.21–6.98]

 

 III-IV

10.96 [4.70–25.53]

8.61 [3.40–21.78]

 

7.33 [2.48–21.62]

 

SPC

 NOA

ref.

ref.

0.72 [0.27–1.90]

ref.

1.54 [0.15–15.96]a

    

0.53 [0.23–1.24]b

 CMW

1.23 [0.75–2.03]

1.07 [0.57–2.00]

1.05 [0.59–1.88]

1.31 [0.63–2.70]

0.37 [0.12–1.11]a

    

1.19 [0.62–2.30]b

 Farmers

0.72 [0.37–1.39]

0.59 [0.25–1.40]

1.10 [0.63–1.93]

0.85 [0.37–1.94]

0.11 [0.05–0.24]a

    

1.41 [0.69–2.87]b

 OOA

1.17 [0.68–2.03]

1.19 [0.61–2.31]

0.70 [0.41–1.20]

1.24 [0.56–2.76]

0.65 [0.23–1.81]a

    

0.66 [0.38–1.15]b

 AIC

2539

2545

2539

  1. Note: Excess hazard ratio (EHR) with 95% confidence interval (95% CI) are estimated for Models 1, 2 and 3, while α with 95% CI are estimated for Model 2 and 3. Ɛ, Determined breakpoint; CS, Cancer stage; NOA, No occupational activity; CMW, Clerical and manual workers; OOA, Other occupational activities; a Estimate of α before Ɛ; b Estimate of α after Ɛ; AIC, Akaike information criterion