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Table 2 Hazard ratios along with their 95% confidence intervals for the 12 most influential variables for the Cox models. Variables are presented in decreasing order according to the absolute z-score values (12.90 to 5.16) for the Cox model with all variables. Predictors shown are the most prognostic as their z-scores values correspond to low and very significant p-values. These variables were also selected by both Cox backward and Cox LASSO model which verifies their prognostic ability for Cox models

From: Survival prediction models since liver transplantation - comparisons between Cox models and machine learning techniques

  Cox all variables Cox backward Cox LASSO
  HR (95% CI) HR (95% CI) HR
Re-transplantation 1.602 (1.491-1.721) 1.608 (1.501-1.722) 1.558
Donor age 1.010 (1.008-1.011) 1.011 (1.009-1.012) 1.009
Donor type DCD (a) 1.483 (1.362-1.616) 1.443 (1.338-1.556) 1.298
log(Total cold ischemic time) 1.258 (1.192-1.327) 1.285 (1.221-1.353) 1.191
Diabetes 1.173 (1.125-1.225) 1.176 (1.128-1.226) 1.136
Race Black (b) 1.240 (1.171, 1.314) 1.261 (1.193-1.332) 1.186
Life support 1.343 (1.240-1.454) 1.375 (1.272-1.487) 1.304
Recipient age 1.007 (1.005-1.009) 1.008 (1.006-1.010) 1.006
Incidental tumour 1.314 (1.202, 1.437) 1.315 (1.203-1.437) 1.203
Hypertensive bleeding 1.296 (1.185, 1.418) 1.301 (1.190-1.423) 1.214
HCV (c) serology status 1.147 (1.091-1.206) 1.148 (1.094-1.205) 1.166
Pre-treatment status ICU (d) 1.240 (1.143, 1.346) 1.253 (1.160-1.354) 1.164
  1. (a): Donor type DCD (Donor Circulatory Dead) vs DBD (Donor after Brain-Dead), (b): Race Black vs White, (c): Chronic hepatitis C virus, (d): Intense Care Unit vs Non-hospitalised/Hospitalised