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Fig. 3 | BMC Medical Research Methodology

Fig. 3

From: Improved selection of participants in genetic longevity studies: family scores revisited

Fig. 3

Evaluation of LRC and mLRC as selection tools with simulated data. Distribution of positive predictive (PPV) values across 1000 simulation runs. For each simulation run, the PPV associated to the selection rule under investigation was computed. Black lines represent the results based on LRC and grey lines represent the results based on mLRC. The left panel shows the results when defining the 10% of families with the lowest value of the random effect u as truly long-lived and the selection criterion is declaring families with the 10% largest values of the score as long-lived. The right panel shows the results for the more strict definition of longevity, based on the 5% lowest values of the random effect u and the selection criterion is declaring families with the 5% largest values of the score as long-lived

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