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Table 3 Evaluation of selection strategies of long-lived families based on LRC and mLRC scores in the HSN

From: Improved selection of participants in genetic longevity studies: family scores revisited

Score

β

s.e.

LRC ≥ 0.3

−0.287

0.082

mLRC ≥ 0.15

−0.321

0.084

  1. Long-lived families were defined as those belonging to the top 15% of each score which corresponded to a cut-off of 0.3 in LRC and a cut-off of 0.15 in mLRC. For each binary variable defined in these cut-offs, a multivariable Cox proportional hazard regression model corrected by birth cohort and gender is fitted in the validation set. Estimates of the resulting regression coefficient(β) and standard error (s.e.) are reported
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