| 8-Predictor Model | 17-Predictor Model | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ML | Firth | Ridge | Lasso | Elastic-net | Backward (AIC) | Backward (P <  0.05) | ML | Firth | Ridge | Lasso | Elastic-net | Backward (AIC) | Backward (P <  0.05) | |
Coefficients: | ||||||||||||||
 Intercept | −5.092 | −5.034 | −4.787 | −4.933 | − 4.886 | − 4.927 | − 4.927 | −5.090 | −4.983 | −3.434 | −3.494 | −3.486 | −3.494 | −2.853 |
 Age > 65 years | 1.637 | 1.616 | 1.424 | 1.578 | 1.535 | 1.631 | 1.631 | 1.429 | 1.399 | 1.161 | 1.336 | 1.324 | 1.495 | 1.532 |
 Female gender | 0.622 | 0.620 | 0.592 | 0.586 | 0.586 | 0.624 | 0.624 | 0.490 | 0.487 | 0.380 | 0.288 | 0.289 | 0.368 | . |
 Diabetes | 0.069 | 0.083 | 0.078 | 0.024 | 0.035 | . | . | 0.153 | 0.164 | 0.131 | . | . | . | . |
 Hypotension | 1.218 | 1.215 | 1.102 | 1.164 | 1.145 | 1.252 | 1.252 | 1.192 | 1.178 | 1.037 | 1.036 | 1.030 | 1.230 | 1.227 |
 Tachycardia | 0.650 | 0.645 | 0.574 | 0.608 | 0.597 | 0.661 | 0.661 | 0.653 | 0.643 | 0.533 | 0.530 | 0.526 | 0.669 | 0.717 |
 High risk | 0.847 | 0.835 | 0.748 | 0.796 | 0.781 | 0.855 | 0.855 | 0.403 | 0.397 | 0.390 | 0.372 | 0.372 | 0.414 | 2.748 |
 Shock | 2.395 | 2.362 | 2.339 | 2.362 | 2.354 | 2.424 | 2.424 | 2.685 | 2.608 | 2.508 | 2.460 | 2.455 | 2.662 | 0.779 |
 No relief of chest pain | 0.263 | 0.255 | 0.237 | 0.219 | 0.221 | . | . | 0.233 | 0.223 | 0.200 | 0.107 | 0.107 | . | . |
 Previous MI |  |  |  |  |  |  |  | 0.505 | 0.495 | 0.437 | 0.378 | 0.376 | 0.586 | . |
 Height |  |  |  |  |  |  |  | 0.008 | 0.008 | −0.001 | . | . | . | . |
 Weight |  |  |  |  |  |  |  | −0.019 | −0.018 | −0.015 | −0.014 | −0.014 | −0.018 | −0.023 |
 Hypertension history |  |  |  |  |  |  |  | −0.165 | −0.159 | −0.123 | . | . | . | . |
 Ex-smoker |  |  |  |  |  |  |  | 0.174 | 0.169 | 0.147 | . | . | . | . |
 Current smoker |  |  |  |  |  |  |  | 0.247 | 0.241 | 0.231 | 0.057 | 0.059 | . | . |
 Hypercholesterolemia |  |  |  |  |  |  |  | −0.064 | −0.060 | −0.064 | . | . | . | . |
 Previous angina pectoris |  |  |  |  |  |  |  | 0.246 | 0.243 | 0.235 | 0.151 | 0.151 | . | . |
 Family history of MI |  |  |  |  |  |  |  | −0.015 | −0.014 | −0.036 | . | . | . | . |
 ST elevation in > 4 leads |  |  |  |  |  |  |  | 0.583 | 0.571 | 0.479 | 0.434 | 0.430 | 0.601 | 0.752 |
C-statistics: | ||||||||||||||
 Apparent | 0.819 | 0.819 | 0.819 | 0.819 | 0.819 | 0.820 | 0.820 | 0.832 | 0.832 | 0.831 | 0.831 | 0.831 | 0.829 | 0.824 |
 Harrell | 0.810 | 0.810 | 0.812 | 0.810 | 0.810 | 0.811 | 0.810 | 0.811 | 0.811 | 0.812 | 0.812 | 0.812 | 0.810 | 0.806 |
 .632 | 0.811 | 0.811 | 0.812 | 0.811 | 0.810 | 0.811 | 0.809 | 0.811 | 0.811 | 0.813 | 0.813 | 0.813 | 0.809 | 0.808 |
 .632+ | 0.810 | 0.811 | 0.812 | 0.811 | 0.810 | 0.811 | 0.809 | 0.810 | 0.810 | 0.812 | 0.812 | 0.812 | 0.809 | 0.808 |