Table 3 Posterior median (and 95% CrI) and bias (and width of 95% CrI) for common Ï„2
small Ï„2 | moderate MOD | large MOD | |||
trial size | frequency | one-stage | two-stage | one-stage | two-stage |
small | low | 0.13 (6 × 10− 3, 2.59) 0.11 (2.58) | 0.10 (6 × 10− 3, 1.14) 0.08 (1.13) | 0.13 (6 × 10− 3, 3.06) 0.11 (3.06) | 0.10 (6 × 10− 3, 1.20) 0.08 (1.19) |
moderate | low | 0.07 (4 × 10− 3, 0.70) 0.05 (0.70) | 0.07 (5 × 10− 3, 0.64) 0.05 (0.63) | 0.08 (5 × 10− 3, 0.97) 0.07 (0.96) | 0.08 (5 × 10− 3, 0.82) 0.06 (0.81) |
small | frequent | 0.09 (5 × 10− 3, 0.94) 0.07 (0.93) | 0.08 (5 × 10− 3, 0.83) 0.06 (0.82) | 0.09 (5 × 10− 3, 1.04) 0.07 (1.03) | 0.09 (6 × 10− 3, 0.91) 0.06 (0.90) |
moderate | frequent | 0.04 (3 × 10− 3, 0.31) 0.02 (0.31) | 0.04 (4 × 10− 3, 0.32) 0.02 (0.31) | 0.05 (4 × 10− 3, 0.40) 0.03 (0.40) | 0.05 (4 × 10− 3, 0.42) 0.03 (0.42) |
substantial Ï„2 | moderate MOD | large MOD | |||
trial size | frequency | one-stage | two-stage | one-stage | two-stage |
small | low | 0.13 (6 × 10− 3, 2.52) 0.05 (2.51) | 0.10 (6 × 10− 3, 1.16) 0.02 (1.15) | 0.14 (6 × 10− 3, 3.29) 0.06 (3.29) | 0.10 (6 × 10− 3, 1.21) 0.02 (1.21) |
moderate | low | 0.09 (5 × 10− 3, 1.05) 0.01 (1.05) | 0.08 (5 × 10− 3, 0.86) 0.004 (0.85) | 0.09 (5 × 10− 3, 1.17) 0.02 (1.17) | 0.08 (5 × 10− 3, 0.90) 0.01 (0.89) |
small | frequent | 0.10 (5 × 10− 3, 1.15) 0.02 (1.14) | 0.09 (6 × 10− 3, 0.95) 0.01 (0.95) | 0.10 (5 × 10− 3, 1.26) 0.02 (1.25) | 0.09 (6 × 10− 3, 1.01) 0.01 (1.01) |
moderate | frequent | 0.06 (4 × 10− 3, 0.57) −0.02 (0.57) | 0.05 (4 × 10− 3, 0.56) − 0.02 (0.56) | 0.06 (4 × 10− 3, 0.58) − 0.02 (0.57) | 0.06 (4 × 10− 3, 0.56) − 0.02 (0.56) |