Skip to main content

Table 2 GRADE assessment of the included studies

From: A systematic review of methodology used in the development of prediction models for future asthma exacerbation

Number of studies Certainty assessment Certainty Importance
Study design Risk of bias Inconsistency Indirectness Imprecision Other considerations
Exacerbation
 5 Observational studies Not serious Not serious Not serious Not serious None
HIGH
CRITICAL
Risk (Categorical)
 2 Observational studies Not serious Not serious Not serious Not serious None
LOW
CRITICAL
Time to first severe exacerbation
 1 Observational studies Not serious Not serious Not serious Not serious Publication bias strongly suspected dose response curvea
HIGH
CRITICAL
Asthma admissions
 1 Observational studies Not serious Not serious Not serious Not serious None
HIGH
IMPORTANT
Relapse
 1 Observational studies Not serious Not serious Not serious Not serious None
HIGH
IMPORTANT
  1. aContributions from pharmaceutical company employees