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Table 2 Results of extrapolating early-pregnancy weights in Study I and interpolating early-pregnancy weights in Study II

From: Methodological approaches to imputing early-pregnancy weight based on weight measures collected during pregnancy

Imputation method

Mean Absolute Error (kg)

Study I weight extrapolation

N=1472

Study II weight interpolation

N=2131

Mixed-effects models

All weights included (n=6272)

Dropping third trimester weights (n=3375)

All weights included (n=11,775)

Dropping third trimester weights (n=8125)

 3 knots (quartiles)

1.99

2.01

1.69

1.64

 4 knots (quintiles)

2.08

2.05

1.66

1.59

 5 knots (sextiles)

2.18

N/Aa

1.60

1.70

 3 knots (5th, 50th, 95th)

2.00

2.00

1.67

1.63

 4 knots (5th, 35th, 65th, 95th)

2.00

1.98

1.62

1.66

 5 knots (5th, 27.5th, 50th, 72.5th, 95th)

2.25

1.98

1.60

1.81

 Linear

2.02

2.01

1.67

1.65

 Quadratic

2.02

1.95

1.66

1.62

 Cubic

2.02

6.46

1.62

N/Aa

Marginal models with GEE

Mean residual

Nearest weight residual

Mean residual

Nearest weight residual

 3 knots (quartiles)

2.94

3.94

2.03

1.98

 4 knots (quintiles)

2.94

3.94

2.00

1.97

 5 knots (sextiles)

2.94

3.94

1.96

1.96

 3 knots (5th, 50th, 95th)

2.94

3.94

2.02

1.97

 4 knots (5th, 35th, 65th, 95th)

2.94

3.93

1.97

1.96

 5 knots (5th, 27.5th, 50th, 72.5th, 95th)

2.94

3.92

1.95

2.01

 Linear

2.94

3.94

2.01

2.03

 Quadratic

2.94

3.94

2.02

1.98

 Cubic

2.93

3.92

1.97

1.96

Assigning the nearest weight measure

2.46

2.14

Arithmetic imputation using the nearest two weight measures

2.91

2.00

  1. Abbreviations: GEE generalized estimating equation
  2. aModel failed to converge