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Table 2 Scenarios 1-6 in the simulation study. Doses with dose limiting toxicities in the targeted toxicity interval (0.20 - 0.40) are in boldface. Scenarios 1-6 represent phase I trials with one schedule, that is daily schedule

From: Phase I dose-escalation oncology trials with sequential multiple schedules

  Doses in mg
Scenario 2.5 5 7.5 10 12.5 15
1 0.05 0.10 0.20 0.30 0.50 0.70
2 0.30 0.40 0.52 0.61 0.76 0.87
3 0.05 0.06 0.08 0.11 0.19 0.34
4 0.06 0.08 0.12 0.18 0.40 0.71
5 0.10 0.22 0.31 0.45 0.60 0.72
6 0.50 0.55 0.61 0.69 0.76 0.87