Skip to main content

Table 3 Coefficient estimates across the IPD-AgD NMA of all models considered in the analysis for viral suppression at 48 weeks as an outcome

From: Comparing the use of aggregate data and various methods of integrating individual patient data to network meta-analysis and its application to first-line ART

Analyses Model ß1,1
Median
(95% CrI)
ß1,2
Median
(95% CrI)
ß1,3
Median
(95% CrI)
ß0,1
Median
(95% CrI)
ß0,2
Median
(95% CrI)
ß0,3
Median
(95% CrI)
AgD NMA meta-regression – CD4 Fixed 0.096 (−0.039, 0.216)
AgD NMA meta-regression – HIV RNA Fixed 0.009 (− 0.368, 0.377)
AgD NMA meta-regression – Male Fixed 0.041 (− 0.947, 1.035)
One-stage IPD-AgD NMA – CD4 + HIV RNA + Male Fixed 0.144 (0.015, 0.272) −0.031 (− 0.363, 0.296) −0.237 (− 0.957, 0.429) −0.779 (−3.481, 1.729) 0.256 (−9.87, 7.315) −7.108 (−20.194, 17.658)
One-stage IPD-AgD NMA – CD4 + Male Fixed 0.135 (0.011, 0.264) − 0.019 (− 0.338, 0.303) 0.174 (− 2.918, 2.76) −1.272 (−6.477, 3.456)
One-stage IPD-AgD NMA – CD4 + HIV RNA Fixed 0.149 (0.035, 0.269) −0.229 (− 0.945, 0.427) −0.413 (− 2.778, 1.985) −2.913 (− 10.851, 4.943)
One-stage IPD-AgD NMA – HIV RNA + Male Fixed −0.195 (− 0.486, 0.097) −0.105 (− 0.791, 0.539) 8.999 (− 0.415, 15.519) −19.637 (− 32.557, − 6.818)
One-stage IPD-AgD NMA – CD4 Fixed 0.139 (0.028, 0.251) 0.351 (− 1.398, 2.058)
One-stage IPD-AgD NMA – HIV RNA Fixed −0.182 (− 0.468, 0.104) −0.500 (− 4.586, 3.167)
One-stage IPD-AgD NMA – Male Fixed − 0.014 (− 0.674, 0.607) 1.347 (− 10.007, 6.357)