Fig. 3From: Intention-to-treat analysis may be more conservative than per protocol analysis in antibiotic non-inferiority trials: a systematic reviewGraphical comparison of ITT versus PP point estimate. ARR = absolute risk reduction; ITT = intention-to-treat; PP = per protocol. The size of the points on the graph is proportional to the sample size of the ITT population. A diagonal line is drawn at y = x, so ITT analysis is more conservative for points above the line and PP analysis is more conservative for points below the lineBack to article page