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Table 3 Estimated prevalence of neurodevelopmental impairment after corrections for loss to follow-up using inverse probability weighting (IPW) and multiple imputation (MI)

From: Strategies for assessing the impact of loss to follow-up on estimates of neurodevelopmental impairment in a very preterm cohort at 2 years of age

  Portugal UK Total
Crude 16.5 [13.1;20.5] 20.0 [16.6;24.0] 18.4 [15.9;21.2]
IPW complete cases 17.5 [14.4;21.1] 20.5 [17.9;23.3] 19.4 [17.4;21.6]
 % Change in prevalencea 6.1% 2.5% 5.4%
IPW imputed cases 18.3 [14.1;22.6] 20.8 [16.7;25.0] 20.0 [16.9;23.1]
 % Change in prevalence 10.9% 4.0% 8.7%
MI (total population) 17.4 [13.4;21.4] 21.9 [17.9;26.0] 20.4 [17.3;23.4]
 % Change in prevalence 5.5% 9.5% 10.9%
MI (Responders) 17.1 [13.3;20.8] 19.7 [16.1;23.4] 18.6 [16.0;21.2]
 % Change in prevalence 3.6% −1.5% 1.1%
MI (Non-responders) 18.1 [8.9;27.2] 23.9 [17.2;30.6] 23.0 [17.4;28.7]
  1. MI models were adjusted for gestational age, multiple pregnancy, foreign-born mother or foreign ethnicity, mother's age, parity, breastfeeding at discharge, previous cesarean section, PPROM, antepartum hemorrhage, sex, Apgar at 5 min less than 7, any respiratory support, surfactant, bronchopulmonary dysplasia, any severe morbidity, congenital anomaly, surgery in neonatal unit, hospitalized in a level III unit, SES status, region and follow-up
  2. IPW model were adjusted for multiple pregnancy, foreign-born mother or foreign ethnicity, mother's age, parity, breastfeeding at discharge, previous cesarean section, PPROM, respiratory support MV and CPAP, surfactant, hospitalized in a level III unit, SES status and region
  3. apercent increase in estimated prevalence corrected for selection bias compared to the crude estimate