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Table 2 Summary of the scenario considered for the ARREST trial based on estimations from the raw data

From: Using the geometric average hazard ratio in sample size calculation for time-to-event data with composite endpoints

β1

β2

ρ

gAHR(12)

Events

\({p_{*}^{(a)}}\)

N

Emp. Power

0.70

0.91

0.1

0.788

555

0.171

3,238

0.805

  1. gAHR(12): geometric Average Hazard Ratio; \(\boldsymbol {p}_{*}^{\boldsymbol {(a)} }\): Probability of observing composite event; N: Sample size rounded to an even number
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BMC Medical Research Methodology

ISSN: 1471-2288

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