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Fig. 1 | BMC Medical Research Methodology

Fig. 1

From: Evaluation by simulation of clinical trial designs for evaluation of treatment during a viral haemorrhagic fever outbreak

Fig. 1

Outbreak timeline and specific cases simulated. Three specific cases of outbreak timeline were simulated: “standard” specific case with a fixed control survival rate; “Changing with time” specific case with an increase of the control survival rate over time; and “stopping of recruitment” specific case with a fixed control survival rate and an early stop of the trial due to an outbreak end. Several sample sizes were simulated for the “stopping of recruitment” case: NSTOP = 100, NSTOP = 50, and NSTOP = 20

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