Table 3 Simulation study results of M4, model with shared individual-specific CV parameter (data simulated using M4, 200 datasets of N=200)
From: Dynamic prediction based on variability of a longitudinal biomarker
Parameter | True Value | Mean | SD |
|---|---|---|---|
b1 | -0.03 | -0.029 | 0.008 |
b0 | 7 | 7.006 | 0.102 |
ρ | -0.03 | -0.001 | 0.088 |
\(\sigma ^{2}_{0}\) | 1.75 | 1.769 | 0.204 |
\(\sigma ^{2}_{1}\) | 0.004 | 0.004 | 0.001 |
β0 | -2 | -2.006 | 0.344 |
β1 (HLA Mismatch Number) | 0.25 | 0.265 | 0.085 |
α | 0.5 | 0.516 | 0.04 |
λ0 | -0.5 | -0.551 | 0.289 |
λ2 (loading parameter for individual-specific CV) | 0.2 | -0.179 | 0.480 |