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Table 3 Pathways selected in the final model by LASSO

From: Classification of PR-positive and PR-negative subtypes in ER-positive and HER2-negative breast cancers based on pathway scores

Feature

Estimate

(Intercept)

1.27457

Class_C/3_(Metabotropic_glutamate/pheromone_receptors)

-0.03500

FOXA1_transcription_factor_network

0.10619

Signaling_by_Type_1_Insulin-like_Growth_Factor_1_Receptor_(IGF1R)

0.21581

Amino_acid_transport_across_the_plasma_membrane

-0.01470

Sema3A_PAK_dependent_Axon_repulsion

-0.07956

Na_/Cl-_dependent_neurotransmitter_transporters

0.02917

Metal_ion_SLC_transporters

0.05884

IGF-1_signaling_pathway

0.09220

Signaling_by_constitutively_active_EGFR

-0.04876

Reduction_of_cytosolic_Ca___levels

-0.13606

NOTCH1_Intracellular_Domain_Regulates_Transcription

-0.04873

Synthesis_of_Leukotrienes_(LT)_and_Eoxins_(EX)

0.06633

Activation_of_C3_and_C5

0.23174