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Table 3 Details of third outcomes for meta-analyses

From: Multivariate meta-analysis of critical care meta-analyses: a meta-epidemiological study

Meta_analysis Reference Study Second_outcome Third_outcome Year Third outcome RCT no. Third outcome total patients Third outcome total events I^2 Third outcome sse graphics Third outcome sse test
Griesdale [34] Bivariate Hypoglcaemia   2009       
Annane [35] Bivariate Shock reversal   2009       
Bangalore [36] Trivariate Non-fatal MI Non-fatal stroke 2008 13 11,233 55 0.00 ok 0.260
Marik [37] Trivariate Infection Hospital LOS 2008 4 835 N/A 76.21 query 0.002
Marik [37] Trivariate Hospital LOS Infection 2008 4 144 74 0.00 ok 0.596
Marik [37] Trivariate Hospital LOS Infection 2008 7 300 120 60.37 ok 0.710
Chan [38] Trivariate VAP MV length 2007 5 1597 N/A 23.90 ok 0.400
Gonzalez [39] Bivariate Rebleeding   2008       
Ho [40] Trivariate Pneumonia ICULOS 2006 5 336   0.00 ok 0.410
Ho [41] Bivariate ICU LOS   2008       
Siempos [42] Bivariate VAP   2010       
Singh [43] Bivariate Pneumonia   2009       
Peterson [44] Bivariate Neurological outcome   2008       
Silvestri [45] Bivariate infection   2007       
Whitlock [46] Trivariate New Atrial fibrillation Bleed post-operative 2008 4 513 N/A 7.89 ok 0.120
Piccini [47] Trivariate CVS death Cardiomyopathy 2009 15 8522 1607 3.39 ok 0.228
Landoni [48] Bivariate MI   2010       
Brar [49] Trivariate MI TVR 2009 13 7352 561 35.99 query 0.001
Landoni [50] Trivariate Acute kidney injury Hospital LOS 2007 8 695 N/A 0.00 ok 0.693
Mazaki [51] Bivariate Infection   2008       
Masip [52] Bivariate Intubation   2005       
Oldani [53] Trivariate Infection Hospital LOS 2015 15 2297 N/A 59.35 query 0.710
Szakmany [54] Trivariate VAP MV length 2015 9 1623 N/A 76.73 query 0.532
Alkhawaja [55] Trivariate Pneumonia ICU LOS 2015 6 484 N/A 17.63 ok 0.208
Van Zanten [56] Trivariate Infection Hospital LOS 2015 6 535 N/A 61.28 query 0.540
Wan [57] Bivariate Hospital LOS MV length 2015 7 617 N/A 88.84 query 0.562
Teo [58] Bivariate Clinical response   2014       
Manzanares [59] Trivariate Infection MV length 2012 5 368 N/A 65.48 query 0.510
Tian [60] Trivariate Pneumonia Hospital LOS 2018 8 517 N/A 12.46 ok 0.624
Rhodes [61] Bivariate Cinical cure   2018       
Nunez-Patino [62] Trivariate Neurological outcome ICU LOS 2018 5 763   0.00 ok 0.194
Kawano-Dourado [63] Bivariate RRT   2018       
Dallimore [64] Bivariate ICU LOS   2018       
Chong [65] Bivariate Myocardial infarction   2018       
Yang [66] Trivariate Renal function recovery RRT time 2017 3 576   97.92 query 0.003
Osadnik [67] Trivariate Hospital LOS MV 2017 12 846 196 84.57 query 0.043
Lu [68] Trivariate ICU LOS MV length 2017 7 495 N/A 67.15 ok 0.680
Chen [69] Trivariate ICU LOS RRT 2017 8 1908 129 0.00 ok 0.413
Qureshi [70] Bivariate Acute kidney injury   2016       
Elke [71] Trivariate Infection Hospital LOS 2016 6 2684 N/A 0.00 ok 0.686
Parikh [72] Trivariate Hospital LOS ICU LOS 2016 10 2782 421 50.85 ok 0.396
Davies [73] Trivariate VAP Hospital LOS 2017 10 2747 N/A 72.54 ok 0.340
Abroug [74] Bivariate Clinical response   2014       
Manzanares [75] Bivariate infection   2016       
Peter [76] Trivariate Mechanical ventilation Hospital LOS 2002 10 398 N/A 88.06 query 0.246
Wang [77] Trivariate Rebleeding Surgery 2010 5 949 22 0.00 ok 0.570
Tao [78] Trivariate Infection MV length 2016 4 288 N/A 52.89 query 0.036
Tang [79] Trivariate Antibiotic exposure ICU LOS 2009 6 1386 N/A 99.01 query 0.674
Muscedere [80] Trivariate VAP MV length 2011 4 458 N/A 6.27 ok 0.412
  1. LOS Length of stay (days), ICU Intensive care unit, VAP Ventilator associated pneumonia, CVS Cardiovascular, MV Mechanical ventilation, TVR Target vessel revascularization, RRT Renal replacement therapy, MI Myocardial infarction, Ok Visual assessment of contour-enhanced revealed no problematic asymmetry, query Visual assessment of contour-enhanced revealed problematic asymmetry