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Fig. 2 | BMC Medical Research Methodology

Fig. 2

From: Modeling of atrophy size trajectories: variable transformation, prediction and age-of-onset estimation

Fig. 2

Determination of the optimal Box-Cox transformation. For each value of the transformation parameter λ, parametric mixed-effects models A without covariables as in Model (3) and B with covariables as in Model (6) were fitted to the analysis data set. Model fitting was performed using the R package lme4. The orange dot indicates the optimal fit, which was achieved at λopt=0.45. For Model (3), the optimal AIC value was AICλ=0.45=1413.69 and for Model (6) the optimal AIC value was AICλ=0.45=1347.78

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BMC Medical Research Methodology

ISSN: 1471-2288

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