Subgroup | Comparator datasets | P-value | Rating of tests relative to each other |
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MWU | Adj. OLR | WR | OLR | BS | Adj. MLR | Adj. BLR | Adj. CPH | TT | CAT | CPH | MT | CSB | CSO | CSF |
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Trial type |
 Primary | 15 | < 0.0001 | 1 | 6 | 3 | 7 | 8 | 4 | 9 | 12 | 5 | 2 | 11 | 10 | 13 | 15 | 14 |
Secondary | 20 | < 0.0001 | 1 | 4 | 5 | 3 | 2 | 9 | 10 | 12 | 6 | 8 | 11 | 7 | 14 | 13 | 15 |
Main Intervention |
 ACT | 10 | 0.0089 | 1 | 9 | 3 | 7 | 10 | 5 | 6 | 11 | 4 | 2 | 8 | 14 | 13 | 12 | 15 |
 AHT | 6 | 0.011 | 3 | 9 | 7 | 8 | 1 | 4 | 6 | 10 | 2 | 5 | 11 | 13 | 12 | 15 | 14 |
 APT | 10 | < 0.0001 | 1 | 2 | 9 | 3 | 4 | 7 | 12 | 11 | 6 | 8 | 10 | 5 | 14 | 13 | 15 |
 CEA | 2 | < 0.0001 | 5 | 3 | 6 | 4 | 1 | 7 | 11 | 14 | 8 | 9 | 13 | 2 | 12 | 10 | 15 |
 HRT | 2 | 0.35 | 4 | 2 | 1 | 5 | 10 | 3 | 12 | 6 | 7 | 8 | 11 | 9 | 13 | 15 | 14 |
 Statins | 4 | 0.0011 | 1 | 3 | 4 | 2 | 6 | 9 | 12 | 8 | 11 | 7 | 10 | 5 | 13 | 14 | 15 |
- The numbers in bold represent the tests are the most efficient and do not differ statistically from one another. The P-value is from the results of the Friedman ANOVA. The order of the rating of test is based on the mean rank calculated by the Duncan’s multiple range test; the most efficient test (i.e. the test with the smallest mean rank) is rated the best with a score of 1 and the least efficient with a score of 15
- Abbreviations
- ACT: anticoagulants;Â Adj.: adjusted;Â AHT: antihypertensives;Â APT: antiplatelets;Â BLR: binary logistic regression;Â BS: bootstrapping;Â CAT: Cochran-Armitage Trend test;Â CEA: carotid Endarterectomy;Â CPH: Cox proportional hazards;Â CSB: Chi-square binary event outcome;Â CSF: Chi-square binary fatal event outcome;Â CSO: Chi-square ordinal event outcome;Â HRT: hormone replacement therapy;Â MWU: Mann-Whitney U test;Â MT: median test;Â MLR: multiple linear regression;Â OLR: ordinal logistic regression;Â TT: t-test;Â Vascular: combination of stroke and MI;Â WR: win ratio test