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Table 1 Description of the four adaptive interventions (AI). N = Nurse, A = App and A + N = App + Nurse

From: Sequential Multiple Assignment Randomized Trial (SMART) to identify optimal sequences of telemedicine interventions for improving initiation of insulin therapy: A simulation study

AI# Notation Description
AI1 (N, NRA1 − R) Nurse at stage 1, continue with Nurse at stage 2 if responder, or switch to App at stage 2 if non-responder.
AI2 (N, NR(A + N)1 − R) Nurse at stage 1, continue with Nurse at stage 2 if responder, or provide combination at stage 2 if non-responder.
AI3 (A, ARN1 − R) App at stage 1, continue with App at stage 2 if responder, or switch to Nurse at stage 2 if non-responder.
AI4 (A, AR(A + N)1 − R) App at stage 1, continue with App at stage 2 if responder, or provide combination at stage 2 if non-responder.